Komori
Other Disclosures4929ADJUVANT HOLDINGS CO.,LTD.Materials and Chemicals

Joint development of nanoscale particles for cosmetics that deliver beauty ingredients to mitochondria

アジュバンコスメジャパン and Hokkaido University jointly conducted research and developed particles that deliver beauty ingredients to the vicinity of mitochondria using cosmetic ingredients. They established conditions for the stable, large-scale preparation of particles approximately 100 nm in diameter and confirmed mitochondrial accumulation and other properties in cell experiments.

Worth reading
75Important
0–100. This measures how worthwhile something is to read, not how good or bad the company is.
Direction
Improvement
Direction inferred from the company’s description.
Scale
100
nm (approximate particle diameter)
Wording
Conditional
How definitive the wording is.

Announced details

Nanoscale particles for cosmetic use (based on the MITO-Porter delivery concept)
Applicable field (uses covered by this announcement)

Cosmetics and anti-aging care products for skin and hair

Contract DateFebruary 2022 (start of joint research)
What the company reported numerically
Quantitative Effects

Particles approximately 100 nm in diameter. Uptake by human dermal fibroblasts and accumulation and colocalization in the vicinity of mitochondria were confirmed. The results indicated the potential to suppress increases in mitochondrial reactive oxygen species in cells exposed to oxidative stress.

Relationship between the counterparty and the company
ADJUVANT HOLDINGS CO.,LTD.4929
Relationship with the Company

Joint research with the company’s subsidiary, 株式会社アジュバンコスメジャパン. Joint research began in February 2022.

CounterpartyNational University Corporation Hokkaido University, Graduate School of Pharmaceutical Sciences, Professor Yamada Yuma (山田勇磨)

Professor at Hokkaido University’s Graduate School of Pharmaceutical Sciences. Other information, including location, representative, capital and year of establishment, is Not disclosed

Registration number and expiry date

Patent registration No. 5067733 (MITO-Porter)

Location (as indicated in this announcement)

株式会社アジュバンコスメジャパン: Chuo-ku, Kobe, Hyogo Prefecture

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

Related research presented at the 145th Annual Meeting of the Pharmaceutical Society of Japan (March 2025, Fukuoka)

Announced details
ItemDetails
Names of Products / Services CoveredNanoscale particles for cosmetic use (based on the MITO-Porter delivery concept)
CounterpartyNational University Corporation Hokkaido University, Graduate School of Pharmaceutical Sciences, Professor Yamada Yuma (山田勇磨)
Counterparty overviewProfessor at Hokkaido University’s Graduate School of Pharmaceutical Sciences. Other information, including location, representative, capital and year of establishment, is Not disclosed
Relationship with the CompanyJoint research with the company’s subsidiary, 株式会社アジュバンコスメジャパン. Joint research began in February 2022.
Contract DateFebruary 2022 (start of joint research)
Applicable areaCosmetics and anti-aging care products for skin and hair
Registration number and expiry datePatent registration No. 5067733 (MITO-Porter)
Location株式会社アジュバンコスメジャパン: Chuo-ku, Kobe, Hyogo Prefecture
Quantitative EffectsParticles approximately 100 nm in diameter. Uptake by human dermal fibroblasts and accumulation and colocalization in the vicinity of mitochondria were confirmed. The results indicated the potential to suppress increases in mitochondrial reactive oxygen species in cells exposed to oxidative stress.
SourceRelated research presented at the 145th Annual Meeting of the Pharmaceutical Society of Japan (March 2025, Fukuoka)
Items this document does not state (8)
Contract ValueOffering priceLaunch dateAward/certification nameAwarding / certifying bodyLocation scaleUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The project focused on the close relationship between declining mitochondrial function and the aging process. A technology was needed to deliver “Ingredient X” efficiently so that it could exert its function in mitochondria.

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Joint development of nanoscale particles for cosmetics that deliver beauty ingredients to mitochondria | ADJUVANT HOLDINGS CO.,LTD. (4929) timely disclosure | Komori