Establishing regenerative-inducing medicines that activate patients' own stem cells
First written in FY2019. 14 of 17 entries say "Restated". Latest entry: 2026-09-11.
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- FY2026-H1RestatedAnnual report
「Unlike conventional regenerative medicine, regenerative-inducing medicines® are pharmaceuticals based on an entirely new mechanism of action that achieves regenerative medicine by inducing the accumulation of mesenchymal stem cells in the patient’s own body through drug administration, without requiring the transplantation or administration of cells artificially cultured outside the body.」
The mechanism of regenerative-inducing medicines, using the patient’s own mesenchymal stem cells through drug administration without living cells, has been reaffirmed. - FY2025RestatedAnnual report
「Unlike conventional regenerative medicine (Note 1) and cell therapy, regenerative-inducing medicines® do not require the administration of living cells. By administering a substance, namely a pharmaceutical product, they activate stem cells (Note 2) already present in the patient’s body, enabling regenerative medicine with greater convenience, safety and therapeutic efficacy.」
The mechanism of activating the patient’s own stem cells through drug administration, without administering living cells, has been reaffirmed. - FY2024RestatedAnnual report
「Unlike conventional regenerative medicine, regenerative-inducing medicines® are pharmaceuticals based on an entirely new mechanism of action that achieves regenerative medicine by inducing the accumulation of mesenchymal stem cells in the patient’s own body through drug administration, without requiring the transplantation or administration of cells artificially cultured outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2024-Q3RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2024-Q1RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2023-Q1RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2022RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2022-Q1RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2021RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of using the patient’s own stem cells through drug administration, without culturing or transplanting cells outside the body, has been reaffirmed. - FY2021-Q3RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of regenerative-inducing medicines is reaffirmed: the patient's own stem cells are harnessed through drug administration without cell transplantation. - FY2021-Q2RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of regenerative-inducing medicines is reaffirmed: the patient's own stem cells are harnessed through drug administration without cell transplantation. - FY2021-Q1RestatedAnnual report
「Unlike conventional regenerative medicine, redasemtide is a pharmaceutical based on an entirely new mechanism of action that promotes the regeneration of damaged tissue by harnessing stem cells within the patient's body through drug administration alone, without any need to transplant or administer cells cultured artificially outside the body.」
The mechanism of regenerative-inducing medicines is reiterated: the patient's own stem cells are harnessed through drug administration without cell transplantation. - FY2020-Q3AdvancedAnnual report
「Because the HMGB1 peptide is broken down and disappears from the body shortly after administration, the fact that its effects persist for more than 6 months after treatment ended is considered evidence in epidermolysis bullosa that the mechanism of regenerative-inducing medicines has been demonstrated: stem cells released from the bone marrow into the bloodstream by the medicine accumulate at the site of injury through the circulating blood and continue to exert their effects over an extended period.」
The persistence of KOI2's effects for more than 6 months after treatment ended is presented as evidence that the mechanism of regenerative-inducing medicines has been demonstrated in epidermolysis bullosa. - FY2020-Q2RestatedAnnual report
「Regenerative-inducing medicines are pharmaceuticals based on a new mechanism of action that promotes the functional regeneration and healing of biological tissues damaged and rendered dysfunctional by injury or disease.」
Regenerative-inducing medicines are described as pharmaceuticals based on a new mechanism of action, reiterating the established technology concept. - FY2019First statedAnnual report
「Unlike conventional regenerative medicine and cell therapy, regenerative-inducing medicines do not require the administration of living cells. Instead, they activate stem cells already present in the patient's body through administration of a substance, namely a pharmaceutical product, thereby providing regenerative medicine in a simpler and safer manner with enhanced therapeutic effects.」
The technology concept involves activating stem cells in the body through drug administration without administering living cells.