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Other Disclosures4599StemRIM Inc.Pharmaceuticals

Notice of Publication of a Paper on a Phase 2 Investigator-Initiated Clinical Trial of Redasemtide (HMGB1 Peptide), a Regeneration-Inducing Drug, for Chronic Liver Disease

A paper on the safety and efficacy of Redasemtide in a previously conducted phase 2 investigator-initiated clinical trial for chronic liver disease was published in May 2026. The paper suggests therapeutic effects including reduced liver injury and improved liver fibrosis.

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Improvement
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Announced details

Redasemtide (HMGB1 peptide, S-005151)
Applicable field (uses covered by this announcement)

Chronic liver disease

What the company reported numerically
Quantitative Effects

The paper suggests therapeutic effects including reduced liver injury and improved liver fibrosis. However, no figures were disclosed.

Relationship between the counterparty and the company
StemRIM Inc.4599
Relationship with the Company

The announcement concerns Redasemtide, our development product. The clinical trial is described as investigator-initiated, but the relationship with the investigators and medical institutions is Not disclosed.

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

Paper published in Inflammation and Regeneration, “Safety and efficacy profile of S-005151 (Redasemtide), in patients with chronic liver diseases: phase 2 trial,” DOI: https://doi.org/10.1186/s41232-026-00421-9

Announced details
ItemDetails
Names of Products / Services CoveredRedasemtide (HMGB1 peptide, S-005151)
Relationship with the CompanyThe announcement concerns Redasemtide, our development product. The clinical trial is described as investigator-initiated, but the relationship with the investigators and medical institutions is Not disclosed.
Applicable areaChronic liver disease
Quantitative EffectsThe paper suggests therapeutic effects including reduced liver injury and improved liver fibrosis. However, no figures were disclosed.
SourcePaper published in Inflammation and Regeneration, “Safety and efficacy profile of S-005151 (Redasemtide), in patients with chronic liver diseases: phase 2 trial,” DOI: https://doi.org/10.1186/s41232-026-00421-9
Items this document does not state (13)
CounterpartyCounterparty overviewContract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

A paper on a previously conducted phase 2 investigator-initiated clinical trial for chronic liver disease was published.

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Notice of Publication of a Paper on a Phase 2 Investigator-Initiated Clinical Trial of Redasemtide (HMGB1 Peptide), a Regeneration-Inducing Drug, for Chronic Liver Disease | StemRIM Inc. (4599) timely disclosure | Komori