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Other Disclosures4599StemRIM Inc.Pharmaceuticals

Update on regenerative medicine drug Redasemtide

ステムリム announced the future development schedule for redasemtide disclosed by Shionogi & Co.,Ltd. For dystrophic epidermolysis bullosa, preliminary results are expected by September 2026, regulatory approval is expected to be filed in the second half of fiscal 2026, and launch is expected in fiscal 2027. For acute ischemic stroke, preliminary results are expected by September 2026, with launch expected between April 2028 and March 2031.

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Announced details

Peptide drug derived from HMGB1, redasemtide; development code: S-005151
Applicable field (uses covered by this announcement)
Dystrophic epidermolysis bullosaAcute ischemic stroke
Relationship between the counterparty and the company
StemRIM Inc.4599
Relationship with the Company

Out-licensed by us to Shionogi & Co.,Ltd.

CounterpartyShionogi & Co.,Ltd.

Head office: Kita-ku, Osaka; Representative Director, Chairman and CEO: Teshirogi Isao (手代木 功)

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

Shionogi & Co.,Ltd., “Fiscal 2025 Financial Results Briefing Materials,” dated 12 May 2026

Announced details
ItemDetails
Names of Products / Services CoveredPeptide drug derived from HMGB1, redasemtide; development code: S-005151
CounterpartyShionogi & Co.,Ltd.
Counterparty overviewHead office: Kita-ku, Osaka; Representative Director, Chairman and CEO: Teshirogi Isao (手代木 功)
Relationship with the CompanyOut-licensed by us to Shionogi & Co.,Ltd.
Applicable areaDystrophic epidermolysis bullosa, Acute ischemic stroke
SourceShionogi & Co.,Ltd., “Fiscal 2025 Financial Results Briefing Materials,” dated 12 May 2026
Items this document does not state (12)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleQuantitative EffectsUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Because Shionogi & Co.,Ltd. disclosed its future research and development schedule.

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Update on regenerative medicine drug Redasemtide | StemRIM Inc. (4599) timely disclosure | Komori