A joint study by Kagome, Hirosaki University and Sysmex showed that health-screening participants with higher skin carotenoid levels had more favorable blood amyloid β42/40 levels. The findings were published in an international academic journal.
A joint study by Hirosaki University, Kagome and Sysmex analyzed the relationship between skin carotenoid levels measured using Veggie Check and blood markers associated with Alzheimer's disease, using health big data from the Iwaki Health Promotion Project.
The study covered 770 participants in the 2024 health screening. Skin carotenoid levels were assessed using Veggie Check®, and five indicators, including blood amyloid β42/40, were examined as blood biomarkers associated with Alzheimer's disease.
Among participants under 60, the high skin-carotenoid group had significantly more favorable blood amyloid β42/40 levels than the low group. When the relationship between age and β42/40 was visualized by skin carotenoid level, a difference equivalent to approximately 4.5–7 years was observed.
The findings are considered potentially relevant to dementia prevention research, and long-term follow-up is expected to verify the relationship between the two indicators. The paper was published in Scientific Reports on 1 October 2026.