Basic information has been published on Diclocular Ophthalmic Solution 0.1%, an ophthalmic drug that suppresses COX and prostaglandin production to reduce inflammation and pain, with use in conjunctivitis and during eye surgery. Its package insert's dosage instructions and precautions are also outlined.
The basic information describes it as a drug that inhibits cyclooxygenase (COX), suppressing prostaglandin production in the body and thereby reducing inflammation and pain. It is primarily intended for the treatment of conjunctivitis and use during eye surgery.
The package insert specifies a preoperative administration schedule: 4 instillations before surgery, at 3 hours, 2 hours, 1 hour and 30 minutes before surgery, followed by 1 drop 3 times a day after surgery.
Serious adverse reactions include shock, anaphylaxis and corneal ulceration. Other possible reactions include diffuse superficial keratitis, corneal erosion, eye pain, itching and a sensation of dryness.
Contraindications and precautions reportedly include avoiding use in patients with a history of hypersensitivity to the ingredients, monitoring to ensure that eye infections are not masked, maintaining intervals between concomitant medicines, and storing the product protected from light.