アイビー化粧品 identified the plant extract kura, which suppresses immune responses, through joint research with multiple university institutions. Kura is considered capable of suppressing immune signaling, including the NF-κB pathway.
This study involved screening plant extracts and analyzing their mechanisms of action with the aim of developing novel herbal medicine resources targeting pathological skin inflammation. Kura (Sophora angustifolia) was identified as a potential inhibitor of key signaling pathways involved in immune responses. The research team evaluated its inhibitory effects using a cell-based assay system.
The kura identified in this study is a leguminous plant and is considered capable of suppressing major immune response pathways, including the NF-κB pathway. The team investigated the possibility that suppression of immune signaling could lead to the suppression of pathological skin inflammation while advancing the elucidation of the underlying mechanisms.
Based on an announcement by アイビー化粧品, the study was conducted jointly by Doshisha University Center for Pathophysiological Analysis, Kogakuin University Faculty of Advanced Engineering, Yamaguchi University Graduate School of Medicine and Health Sciences Research Center, and Doshisha University Faculty of Life and Medical Sciences. Future applications as a functional cosmetic ingredient or topical formulation are anticipated.
The announcement was issued by アイビー化粧品, based in Minato-ku, Tokyo. The company led the joint research, and the findings are positioned as demonstrating the potential of kura as a novel herbal medicine resource for suppressing skin immune responses. Future applications in clinical development and the development of Japanese and Chinese herbal medicine formulations are anticipated.