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Business alliance8129TOHO HOLDINGS CO.,LTD.Trading & Wholesale

Notice of the Execution of a Basic Agreement with ReproCELL Incorporated on the Domestic Distribution of the Stem Cell Product “Stemchymal”

Toho Holdings has entered into a basic agreement with ReproCELL Incorporated concerning the domestic distribution and stable supply of the regenerative medicine product "Stemchymal®" after regulatory approval is obtained, which is currently pending. The parties will discuss and consider a supply system for medical institutions nationwide by leveraging Toho Holdings' pharmaceutical distribution network.

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Agreements reached under this partnership

Business alliance
8129TOHO HOLDINGS CO.,LTD.
Alliance partnerReproCELL Incorporated
Details of the alliance
  1. 1

    A system for supplying medical institutions nationwide by leveraging the pharmaceutical distribution network of the Toho Holdings Group, to achieve the smooth market launch and stable supply of Stemchymal after obtaining marketing approval

  2. 2

    Discuss and consider a distribution system and other arrangements suited to the characteristics of regenerative medicine products

These are items that the documents state the two companies will work on. The lines above and below represent arrangements between the two companies.

About the partner
Business Description① Research support business: manufacture and sale of iPS cell-related research reagents; provision of drug discovery support services; provision of biological samples; provision of genetic analysis services ② Medical business: contract clinical testing services; development of regenerative medicine products
Location3-8-11 Shinyokohama, Kohoku-ku, Yokohama, Kanagawa Prefecture
Share capital¥2,720 million (as of the end of March 2026)
Impact on Business Performance

The impact of this matter on financial results is currently immaterial, but over the medium to long term, we believe it will contribute to improving the corporate value of our group. If the need for timely disclosure arises, we will promptly make an announcement.

Contract Date17 September 2026
Agreements reached under this partnership
ItemDetails
Name of alliance partnerReproCELL Incorporated
Alliance partner's business activities① Research support business: manufacture and sale of iPS cell-related research reagents; provision of drug discovery support services; provision of biological samples; provision of genetic analysis services ② Medical business: contract clinical testing services; development of regenerative medicine products
Alliance partner's location3-8-11 Shinyokohama, Kohoku-ku, Yokohama, Kanagawa Prefecture
Alliance partner's capital¥2,720 million (as of the end of March 2026)
Type of allianceBusiness alliance
Details of the allianceA system for supplying medical institutions nationwide by leveraging the pharmaceutical distribution network of the Toho Holdings Group, to achieve the smooth market launch and stable supply of Stemchymal after obtaining marketing approval, Discuss and consider a distribution system and other arrangements suited to the characteristics of regenerative medicine products
Contract Date17 September 2026
Impact on Business PerformanceThe impact of this matter on financial results is currently immaterial, but over the medium to long term, we believe it will contribute to improving the corporate value of our group. If the need for timely disclosure arises, we will promptly make an announcement.
Items this document does not state (15)
Alliance partner's net salesAlliance partner's operating incomeNumber of shares acquiredAcquisition priceShareholding ratioOverview of the joint ventureOwnership ratioDispatch of directors and officersContract PeriodNumerical targets under the allianceShareholding PolicyDate of board resolutionAlliance start dateShare Acquisition Date and Payment DateChange in major shareholders

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To achieve the smooth market launch and stable supply of Stemchymal® after obtaining marketing approval, together with ReproCELL Incorporated, and to establish a system for stable supply of the product to medical institutions nationwide.

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Notice of the Execution of a Basic Agreement with ReproCELL Incorporated on the Domestic Distribution of the Stem Cell Product “Stemchymal” | TOHO HOLDINGS CO.,LTD. (8129) timely disclosure | Komori