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Other Disclosures4890Tsubota Laboratory IncorporatedPharmaceuticals

MRI confirms changes in brain networks induced by violet light stimulation

Research findings were presented at an academic conference after functional and structural changes in brain networks, including the hippocampus and visual cortex, were confirmed by MRI in model mice replicating a demyelinated state following exposure to violet light. The study did not confirm therapeutic effects in humans and remains at the basic research stage, investigating the mechanism of action.

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Announced details

Violet light, OPN5
Applicable field (uses covered by this announcement)

Central nervous system, research into brain function and structure in demyelinated states, exploration of potential medical applications

What the company reported numerically
Quantitative Effects

Functional and structural changes in brain networks were confirmed in areas including the hippocampus and secondary visual cortex. Specific figures: Not disclosed.

Relationship between the counterparty and the company
Tsubota Laboratory Incorporated4890
Relationship with the Company

A joint research framework receiving the cooperation and advice of the researchers. Details of capital, personnel and business relationships: Not disclosed.

CounterpartyTokyo Metropolitan University, RIKEN, Keio University, Tokyo University of Science, Jikei University School of Medicine

Researchers affiliated with Tokyo Metropolitan University, RIKEN, Keio University, Tokyo University of Science and Jikei University School of Medicine. Location, representative, capital, and year of establishment: Not disclosed.

Impact on Business Performance

No information on the impact on financial results: Not disclosed.

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

54th Annual Meeting of the Japanese Society for Magnetic Resonance in Medicine

Announced details
ItemDetails
Names of Products / Services CoveredViolet light, OPN5
CounterpartyTokyo Metropolitan University, RIKEN, Keio University, Tokyo University of Science, Jikei University School of Medicine
Counterparty overviewResearchers affiliated with Tokyo Metropolitan University, RIKEN, Keio University, Tokyo University of Science and Jikei University School of Medicine. Location, representative, capital, and year of establishment: Not disclosed.
Relationship with the CompanyA joint research framework receiving the cooperation and advice of the researchers. Details of capital, personnel and business relationships: Not disclosed.
Applicable areaCentral nervous system, research into brain function and structure in demyelinated states, exploration of potential medical applications
Quantitative EffectsFunctional and structural changes in brain networks were confirmed in areas including the hippocampus and secondary visual cortex. Specific figures: Not disclosed.
Impact on Business PerformanceNo information on the impact on financial results: Not disclosed.
Source54th Annual Meeting of the Japanese Society for Magnetic Resonance in Medicine
Items this document does not state (10)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleUsage history

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To obtain basic knowledge for elucidating how violet light acts on the brain and the mechanisms involved.

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MRI confirms changes in brain networks induced by violet light stimulation | Tsubota Laboratory Incorporated (4890) timely disclosure | Komori