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Other Disclosures4890Tsubota Laboratory IncorporatedPharmaceuticals

TLM-001, a treatment for meibomian gland dysfunction, achieves LPO in a Phase IIa clinical trial

The final subject observation was completed in the Phase IIa clinical trial of TLM-001 in patients with dry eye disease associated with meibomian gland dysfunction. The clinical data will now be analyzed, and the development strategy will be reviewed.

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Announced details

TLM-001
Applicable field (uses covered by this announcement)

Treatment of dry eye disease associated with meibomian gland dysfunction (MGD)

Launch date25 June 2026 (actual; date of completion of the final subject observation)
Relationship between the counterparty and the company
Tsubota Laboratory Incorporated4890
Relationship with the Company

The trial was conducted by Maruho Co., Ltd., and we received a report confirming completion of the final subject observation. Capital and personnel relationships: Not disclosed.

CounterpartyMaruho Co., Ltd.

Head office: Kita-ku, Osaka; Representative Director and President: Sugita Jun (杉田 淳). Other details: Not disclosed.

Impact on Business Performance

There will be no direct impact on our results for the fiscal year ending March 2027. However, we believe this will contribute to enhancing the value of our pipeline and strengthening the foundation for medium- to long-term growth.

The company does not address Contract Value / Offering price.

Announced details
ItemDetails
Names of Products / Services CoveredTLM-001
CounterpartyMaruho Co., Ltd.
Counterparty overviewHead office: Kita-ku, Osaka; Representative Director and President: Sugita Jun (杉田 淳). Other details: Not disclosed.
Relationship with the CompanyThe trial was conducted by Maruho Co., Ltd., and we received a report confirming completion of the final subject observation. Capital and personnel relationships: Not disclosed.
Launch date25 June 2026 (actual; date of completion of the final subject observation)
Applicable areaTreatment of dry eye disease associated with meibomian gland dysfunction (MGD)
Impact on Business PerformanceThere will be no direct impact on our results for the fiscal year ending March 2027. However, we believe this will contribute to enhancing the value of our pipeline and strengthening the foundation for medium- to long-term growth.
Items this document does not state (11)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleQuantitative EffectsUsage historySource

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The clinical data required to evaluate efficacy and safety have been collected, and the development strategy will now be reviewed.

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TLM-001, a treatment for meibomian gland dysfunction, achieves LPO in a Phase IIa clinical trial | Tsubota Laboratory Incorporated (4890) timely disclosure | Komori