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Other Disclosures4884Kringle Pharma,Inc.Pharmaceuticals

Announcement Regarding a Presentation by Partner クラリス・バイオセラピューティクス社 at the American Academy of Ophthalmology (AAO) 2026 Annual Meeting

Alliance partner Claris Biotherapeutics announced that it is scheduled to give an oral presentation at the AAO Annual Meeting to be held in the United States in October 2026 on improvements in visual acuity with CSB-001 (oremepermin alfa ophthalmic solution) in limbal stem cell deficiency (LSCD). It is also scheduled to give a corporate presentation at a concurrent event.

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Announced details

CSB-001 (oremepermin alfa ophthalmic solution)Recombinant human dHGF protein
Applicable field (uses covered by this announcement)

Ophthalmology; limbal stem cell deficiency (LSCD)

Launch dateOctober 2026 (scheduled presentation at the AAO 2026 Annual Meeting)
Relationship between the counterparty and the company
Kringle Pharma,Inc.4884
Relationship with the Company

Alliance partner. The companies have established a collaborative framework for sharing safety information on recombinant human dHGF protein and optimising the manufacturing process.

CounterpartyClaris Biotherapeutics

An unlisted biotech venture originating from Harvard University in the United States. It is advancing drug development of recombinant human dHGF protein in ophthalmology and conducting clinical trials in the United States for limbal stem cell deficiency and corneal scarring.

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

Claris Biotherapeutics press release (https://www.clarisbio.com/news/press-releases/09-29-2026/)

Announced details
ItemDetails
Names of Products / Services CoveredCSB-001 (oremepermin alfa ophthalmic solution), Recombinant human dHGF protein
CounterpartyClaris Biotherapeutics
Counterparty overviewAn unlisted biotech venture originating from Harvard University in the United States. It is advancing drug development of recombinant human dHGF protein in ophthalmology and conducting clinical trials in the United States for limbal stem cell deficiency and corneal scarring.
Relationship with the CompanyAlliance partner. The companies have established a collaborative framework for sharing safety information on recombinant human dHGF protein and optimising the manufacturing process.
Launch dateOctober 2026 (scheduled presentation at the AAO 2026 Annual Meeting)
Applicable areaOphthalmology; limbal stem cell deficiency (LSCD)
SourceClaris Biotherapeutics press release (https://www.clarisbio.com/news/press-releases/09-29-2026/)
Items this document does not state (11)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleQuantitative EffectsUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Claris Biotherapeutics will present the efficacy of CSB-001 in LSCD at the AAO 2026 Annual Meeting. The company says it will strengthen its collaboration with Claris Biotherapeutics and promote the global development and commercialisation of oremepermin alfa.

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Announcement Regarding a Presentation by Partner クラリス・バイオセラピューティクス社 at the American Academy of Ophthalmology (AAO) 2026 Annual Meeting | Kringle Pharma,Inc. (4884) timely disclosure | Komori