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Other Disclosures4883Modalis Therapeutics CorporationPharmaceuticals

Research findings on MDL-103 for FSHD to be presented at the FSHD Society 2026 International Research Congress

Modalis announced that it plans to present preclinical research data on MDL-103, its development program for FSHD, at an international conference in June 2026. The presentation will show the results of evaluations of DUX4 expression suppression in cells, 3D muscle tissue, and mouse models.

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52Recurring
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Improvement
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Announced details

MDL-103CRISPR-GNDM® technology
Applicable field (uses covered by this announcement)

Therapeutic development for facioscapulohumeral muscular dystrophy (FSHD)

Launch date25–26 June 2026 (scheduled)
What the company reported numerically
Quantitative Effects

Suppression of expression of DUX4 and its target gene group was confirmed and evaluated. The specific suppression rate is not disclosed.

Relationship between the counterparty and the company
Modalis Therapeutics Corporation4883
Relationship with the Company

The organizer of the conference at which the Company will present its research results. Capital and personnel relationships are not disclosed.

CounterpartyFSHD Society

An organization that hosts an international conference featuring research presentations on FSHD. Its location, representative, capital, and year of establishment are not disclosed.

Location (as indicated in this announcement)

Rosemont, Illinois, United States (conference venue)

Impact on Business Performance

No impact on financial results is provided

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

The program for the FSHD Society 2026 International Research Congress and the FSHD Society website

Announced details
ItemDetails
Names of Products / Services CoveredMDL-103, CRISPR-GNDM® technology
CounterpartyFSHD Society
Counterparty overviewAn organization that hosts an international conference featuring research presentations on FSHD. Its location, representative, capital, and year of establishment are not disclosed.
Relationship with the CompanyThe organizer of the conference at which the Company will present its research results. Capital and personnel relationships are not disclosed.
Launch date25–26 June 2026 (scheduled)
Applicable areaTherapeutic development for facioscapulohumeral muscular dystrophy (FSHD)
LocationRosemont, Illinois, United States (conference venue)
Quantitative EffectsSuppression of expression of DUX4 and its target gene group was confirmed and evaluated. The specific suppression rate is not disclosed.
Impact on Business PerformanceNo impact on financial results is provided
SourceThe program for the FSHD Society 2026 International Research Congress and the FSHD Society website
Items this document does not state (8)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleUsage history

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To share research results on MDL-103, which aims to suppress expression of DUX4, the causative gene of FSHD.

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Research findings on MDL-103 for FSHD to be presented at the FSHD Society 2026 International Research Congress | Modalis Therapeutics Corporation (4883) timely disclosure | Komori