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Statutory disclosure document4875MediciNova,Inc.Pharmaceuticals

Notice Regarding Patent Approval in the United States for the Treatment of Glioblastoma with Combination Therapy Using MN-166 (Ibudilast) and the PD-1 Antibody Immune Checkpoint Inhibitor

The Company received a Notice of Allowance from the United States Patent and Trademark Office for methods of treating glioblastoma using MN-166 (ibudilast) in combination with an anti-PD-1 antibody. The patent covers a broad range of treatment conditions, including administration methods and dosages, and is expected to remain valid at least through September 2042.

Worth reading
63In focus
0–100. This measures how worthwhile something is to read, not how good or bad the company is.
Direction
Improvement
Direction inferred from the company’s description.
Scale
2042
Patent validity through at least September 2042 (scheduled)
Wording
Conditional
How definitive the wording is.

Decision and Details

United States Patent and Trademark Office

Notice of allowance for a new patent covering the treatment of glioblastoma using combination therapy with MN-166 (ibudilast) and a PD-1 antibody, an immune checkpoint inhibitor

Decision8 June 2026 (date the notice was received)
Period CoveredAt least through September 2042 (patent validity period)
Quantity / scaleA broad range of treatment conditions, including treatment duration, dosing frequency, route of administration, dosage and dosing schedules; combinations with multiple anti-PD-1 antibodies
Reason

To strengthen the intellectual property foundation for combination therapies related to the Company's development strategy, and to further strengthen the intellectual property portfolio for MN-166 in the field of central nervous system tumors.

Impact on Business Performance

The impact on results for the fiscal year ending December 2026 is expected to be minor.

Decision and Details
ItemDetails
Matter CoveredNotice of allowance for a new patent covering the treatment of glioblastoma using combination therapy with MN-166 (ibudilast) and a PD-1 antibody, an immune checkpoint inhibitor
Decision-Making BodyUnited States Patent and Trademark Office
Decision Date8 June 2026 (date the notice was received)
Period CoveredAt least through September 2042 (patent validity period)
Quantity / scaleA broad range of treatment conditions, including treatment duration, dosing frequency, route of administration, dosage and dosing schedules; combinations with multiple anti-PD-1 antibodies
Impact on Business PerformanceThe impact on results for the fiscal year ending December 2026 is expected to be minor.
ReasonTo strengthen the intellectual property foundation for combination therapies related to the Company's development strategy, and to further strengthen the intellectual property portfolio for MN-166 in the field of central nervous system tumors.
Items this document does not state (5)
Implementation DateAmountGoverning RuleRelated previous disclosuresFuture plans

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To strengthen the intellectual property foundation for combination therapies related to the Company's development strategy.

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Notice Regarding Patent Approval in the United States for the Treatment of Glioblastoma with Combination Therapy Using MN-166 (Ibudilast) and the PD-1 Antibody Immune Checkpoint Inhibitor | MediciNova,Inc. (4875) timely disclosure | Komori