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Other Disclosures4875MediciNova,Inc.Pharmaceuticals

Notice Regarding the Publication of Research Findings on Ibudilast in the International Medical Journal Cancer Research

Research findings from a CNIO research group on ibudilast (MN-166) have been published in the peer-reviewed medical journal Cancer Research. The study indicated that ibudilast may help suppress the progression of brain metastases, and the Company plans to advance clinical research with CNIO and others.

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53Recurring
Scored from 5 of 6 sections
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Improvement
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Announced details

MN-166 (ibudilast)
Applicable field (uses covered by this announcement)
Brain metastases from solid tumorsNeuro-oncology
What the company reported numerically
Quantitative Effects

The progression of brain metastases was significantly suppressed (specific figures are Not disclosed).

Relationship between the counterparty and the company
MediciNova,Inc.4875
Relationship with the Company

The Company announced research findings from a CNIO research group. The Company plans to advance clinical research with CNIO, Dr. Valiente and others. Capital ties, personnel ties and existing business relationships are Not disclosed.

CounterpartySpanish National Cancer Research Centre (CNIO)Dr. Manuel Valiente

CNIO is Spain's national cancer research centre. Dr. Valiente heads CNIO's brain metastasis research group. Other information, including its location, representative, capital and year of establishment, is Not disclosed.

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

Cancer Research (March 2026 issue), paper DOI: 10.1158/0008-5472.CAN-25-4018

Announced details
ItemDetails
Names of Products / Services CoveredMN-166 (ibudilast)
CounterpartySpanish National Cancer Research Centre (CNIO), Dr. Manuel Valiente
Counterparty overviewCNIO is Spain's national cancer research centre. Dr. Valiente heads CNIO's brain metastasis research group. Other information, including its location, representative, capital and year of establishment, is Not disclosed.
Relationship with the CompanyThe Company announced research findings from a CNIO research group. The Company plans to advance clinical research with CNIO, Dr. Valiente and others. Capital ties, personnel ties and existing business relationships are Not disclosed.
Applicable areaBrain metastases from solid tumors, Neuro-oncology
Quantitative EffectsThe progression of brain metastases was significantly suppressed (specific figures are Not disclosed).
SourceCancer Research (March 2026 issue), paper DOI: 10.1158/0008-5472.CAN-25-4018
Items this document does not state (11)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The research indicated that the progression of brain metastases may be suppressed by inhibiting MIF–CD74 signaling and identified potential biomarkers for predicting treatment response.

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Notice Regarding the Publication of Research Findings on Ibudilast in the International Medical Journal Cancer Research | MediciNova,Inc. (4875) timely disclosure | Komori