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Occurring Fact4598Delta-Fly Pharma,Inc.Pharmaceuticals

Notice Regarding Completion of Patient Enrollment for the Phase 2 Portion of the Phase 2/3 Comparative Clinical Trial of DFP-17729

Patient enrollment has been completed in the Phase 2 portion of the Phase 2/3 clinical trial comparing DFP-17729 in combination with TS-1 against monotherapy. The Company plans to proceed to the Phase 3 portion depending on the results of the Phase 2 portion.

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Completion of Patient Enrollment in the Phase 2 Portion of the DFP-17729 Phase 2/3 Comparative Trial

Subject Entity

Delta-Fly Pharma株式会社, NIPPON CHEMIPHAR CO.,LTD.

Target Locations / Products

DFP-17729, an agent that improves the tumor microenvironment, and a Phase 2/3 comparative trial for third-line or later treatment of pancreatic cancer

Awareness or receipt of notice28 May 2026 (the date on which the Company was notified by a participating clinical trial site that patient enrollment had been completed)
This disclosure05/28/2026
Outlook

The number of patients in the Phase 3 portion will be increased or decreased depending on the superiority of overall survival (OS) in the Phase 2 portion, and the Company will proceed promptly to the Phase 3 portion.

Event that occurred
ItemDetails
Event nameCompletion of Patient Enrollment in the Phase 2 Portion of the DFP-17729 Phase 2/3 Comparative Trial
Date recognized / date notice received28 May 2026 (the date on which the Company was notified by a participating clinical trial site that patient enrollment had been completed)
Subject EntityDelta-Fly Pharma株式会社, NIPPON CHEMIPHAR CO.,LTD.
Target Locations / ProductsDFP-17729, an agent that improves the tumor microenvironment, and a Phase 2/3 comparative trial for third-line or later treatment of pancreatic cancer
OutlookThe number of patients in the Phase 3 portion will be increased or decreased depending on the superiority of overall survival (OS) in the Phase 2 portion, and the Company will proceed promptly to the Phase 3 portion.
Items this document does not state (20)
Date of occurrenceCauseAmount of Impact on Business PerformanceAccounting period in which recognizedImpact on Earnings ForecastType of litigation or proceedingCourt or authorityPlaintiffDefendantDate of filing / date of actionClaim amount / surcharge amountAmount of receivables at risk of non-collection or delayed collectionSuspended operationsScheduled resumption dateInvestigation structureMeasures to prevent recurrenceDirectors' and officers' liabilityVoting rights ownership percentage before the changeVoting rights ownership percentage after the changePlanned follow-up disclosure

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The Company was notified by participating clinical trial sites that patient enrollment had been completed.

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Notice Regarding Completion of Patient Enrollment for the Phase 2 Portion of the Phase 2/3 Comparative Clinical Trial of DFP-17729 | Delta-Fly Pharma,Inc. (4598) timely disclosure | Komori