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Other Disclosures4596Kubota Pharmaceutical Holdings Co.,Ltd.Pharmaceuticals

Results of a 12-month pilot study of combination therapy with Kubota Glasses Technology and low-dose atropine presented at Academy 2026 Anaheim

The company announced that it will present the results of a 12-month randomized pilot study combining low-dose atropine and Kubota Glass at the conference scheduled to be held from 30 September to 3 October 2026. The study also presented results including indicators of myopia progression and willingness to use the device in the combination-therapy and atropine-only groups.

Worth reading
74In focus
0–100. This measures how worthwhile something is to read, not how good or bad the company is.
Direction
Neutral
Direction inferred from the company’s description.
Scale
0.28
D (between-group difference in cycloplegic spherical equivalent)
Wording
Conditional
How definitive the wording is.

Announced details

Kubota GlassKubota Glass Technology
Applicable field (uses covered by this announcement)

Pediatric myopia management and suppression of myopia progression

Launch date1 October 2026 (scheduled, poster presentation date)
What the company reported numerically
Quantitative Effects

At 12 months, the mean change in cycloplegic spherical equivalent was −0.35 D in the combination-therapy group and −0.63 D in the atropine-only group, a difference of 0.28 D. Mean axial elongation was 0.25 mm and 0.28 mm, respectively, a difference of 0.03 mm. In the 6-month questionnaire, 94% of respondents said they would be willing to use the device if it could suppress myopia progression.

Usage history

28 study participants at baseline. The 12-month assessment included 15 participants in the combination-therapy group and 8 in the monotherapy group. The 6-month questionnaire included 18 participants.

Relationship between the counterparty and the company
Kubota Pharmaceutical Holdings Co.,Ltd.4596
Relationship with the Company

The company's consolidated subsidiary Kubota Vision Inc. will present the study results at the conference. In terms of capital relationships, Kubota Vision Inc. is the company's consolidated subsidiary.

CounterpartyAmerican Academy of Optometry

An academic organization in optometry and vision science that holds the annual meeting “Academy 2026 Anaheim.” Other information, including its location, representative, capital and year established, is Not disclosed.

Location (as indicated in this announcement)

Hsinchu City, Taiwan: China Medical University Hsinchu Hospital

Impact on Business Performance

The transaction will have no impact on the company's consolidated financial results.

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

Zadnik K, Schulman E, Flitcroft I, et al. JAMA Ophthalmol. 2023

Repka MX, Weise KK, Chandler DL, et al. JAMA Ophthalmol. 2023

Announced details
ItemDetails
Names of Products / Services CoveredKubota Glass, Kubota Glass Technology
CounterpartyAmerican Academy of Optometry
Counterparty overviewAn academic organization in optometry and vision science that holds the annual meeting “Academy 2026 Anaheim.” Other information, including its location, representative, capital and year established, is Not disclosed.
Relationship with the CompanyThe company's consolidated subsidiary Kubota Vision Inc. will present the study results at the conference. In terms of capital relationships, Kubota Vision Inc. is the company's consolidated subsidiary.
Launch date1 October 2026 (scheduled, poster presentation date)
Applicable areaPediatric myopia management and suppression of myopia progression
LocationHsinchu City, Taiwan: China Medical University Hsinchu Hospital
Quantitative EffectsAt 12 months, the mean change in cycloplegic spherical equivalent was −0.35 D in the combination-therapy group and −0.63 D in the atropine-only group, a difference of 0.28 D. Mean axial elongation was 0.25 mm and 0.28 mm, respectively, a difference of 0.03 mm. In the 6-month questionnaire, 94% of respondents said they would be willing to use the device if it could suppress myopia progression.
Usage history28 study participants at baseline. The 12-month assessment included 15 participants in the combination-therapy group and 8 in the monotherapy group. The 6-month questionnaire included 18 participants.
Impact on Business PerformanceThe transaction will have no impact on the company's consolidated financial results.
SourceZadnik K, Schulman E, Flitcroft I, et al. JAMA Ophthalmol. 2023, Repka MX, Weise KK, Chandler DL, et al. JAMA Ophthalmol. 2023
Items this document does not state (7)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scale

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Because study results on the efficacy of low-dose atropine have been mixed, the study examined whether combining treatments with different mechanisms of action could provide a new option for myopia management and sought information useful for planning larger randomized clinical trials in the future.

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Results of a 12-month pilot study of combination therapy with Kubota Glasses Technology and low-dose atropine presented at Academy 2026 Anaheim | Kubota Pharmaceutical Holdings Co.,Ltd. (4596) timely disclosure | Komori