Komori
Other Disclosures4593HEALIOS K.K.Pharmaceuticals

Notice of Research Findings Presentation at the 30th Annual Meeting of the Japanese Association for Cancer Immunology: “Development of Dual CAR-eNK Cells Targeting EGFR and PD-L1 for the Treatment of Malignant Glioma”

HEALIOS announced that it had generated Dual CAR-eNK cells targeting both EGFR and PD-L1 and would present its research results on malignant glioma at the conference. The conference presentation is scheduled for 23 July 2026.

Worth reading
44Recurring
0–100. This measures how worthwhile something is to read, not how good or bad the company is.
Direction
Improvement
Direction inferred from the company’s description.
Scale
—
Displayed only when the document provides numerical figures.
Wording
Conditional
How definitive the wording is.

Announced details

Dual CAR-eNK cells (iPS cell-derived genetically modified NK cells expressing chimeric antigen receptors targeting EGFR and PD-L1), eNK® cells
Applicable field (uses covered by this announcement)

Immune cell therapy for malignant glioma (glioblastoma)

Launch date23 July 2026 (scheduled; poster presentation at the conference)
What the company reported numerically
Quantitative Effects

Enhanced target antigen-specific cytotoxic activity, increased interferon-gamma production capacity, and potent antigen-specific cytotoxic activity against glioblastoma spheroids

Location (as indicated in this announcement)

Kagawa International Conference Hall / Sunport Hall Takamatsu (conference venue); Drug Discovery Research Department, Kobe Research Institute, HEALIOS K.K. (presenter's affiliation)

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

30th Annual Meeting of the Japanese Association for Cancer Immunology (https://med-gakkai.jp/jaci2026/)

Announced details
ItemDetails
Names of Products / Services CoveredDual CAR-eNK cells (iPS cell-derived genetically modified NK cells expressing chimeric antigen receptors targeting EGFR and PD-L1), eNK® cells
Launch date23 July 2026 (scheduled; poster presentation at the conference)
Applicable areaImmune cell therapy for malignant glioma (glioblastoma)
LocationKagawa International Conference Hall / Sunport Hall Takamatsu (conference venue); Drug Discovery Research Department, Kobe Research Institute, HEALIOS K.K. (presenter's affiliation)
Quantitative EffectsEnhanced target antigen-specific cytotoxic activity, increased interferon-gamma production capacity, and potent antigen-specific cytotoxic activity against glioblastoma spheroids
Source30th Annual Meeting of the Japanese Association for Cancer Immunology (https://med-gakkai.jp/jaci2026/)
Items this document does not state (12)
CounterpartyCounterparty overviewRelationship with the CompanyContract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Glioblastoma is highly malignant, has a high recurrence rate, and is often resistant to standard treatment, creating a need for new therapeutic strategies. By simultaneously targeting EGFR and PD-L1, HEALIOS aims to develop a next-generation immune cell therapy suited to glioblastoma.

How to read this page

This is not the documentKomori reads the disclosure the company filed and writes this summary. Figures are as stated by the company and are not audited.
Weight is not a verdictIt measures how much this changes what the company had already told the market. It is not a view on the shares.
Corrections happenIf the company reissues this disclosure, the page is rebuilt from the corrected version and the revision number moves up.
Notice of Research Findings Presentation at the 30th Annual Meeting of the Japanese Association for Cancer Immunology: “Development of Dual CAR-eNK Cells Targeting EGFR and PD-L1 for the Treatment of Malignant Glioma” | HEALIOS K.K. (4593) timely disclosure | Komori