Announced details
Cell therapies and regenerative medicine products for osteonecrosis and intractable bone diseases
At all time points of 4, 6 and 8 weeks after transplantation, the SHED group showed a significantly higher bone repair rate than the scaffold-only group. From 4 weeks after transplantation onward, the SHED group showed a significantly higher bone repair rate than the bone marrow-derived MSC group.
A joint research project that began as a collaboration between S-Quatre and Hokkaido University and subsequently changed from that collaboration to a collaboration with Dokkyo Medical University.
Hokkaido University and Dokkyo Medical University. Other information on their locations, representatives, business activities, capital and year of establishment is Not disclosed.
In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.
Article published in the Journal of Orthopaedic Research, DOI: http://dx.doi.org/10.1002/jor.70263
| Item | Details |
|---|---|
| Names of Products / Services Covered | SHED (referred to within the Group as SQ-SHED; stem cells from human exfoliated deciduous teeth) |
| Counterparty | Hokkaido University, Dokkyo Medical University |
| Counterparty overview | Hokkaido University and Dokkyo Medical University. Other information on their locations, representatives, business activities, capital and year of establishment is Not disclosed. |
| Relationship with the Company | A joint research project that began as a collaboration between S-Quatre and Hokkaido University and subsequently changed from that collaboration to a collaboration with Dokkyo Medical University. |
| Contract Date | 30 September 2024 (joint research agreement signed for the development of a novel treatment for ischemic bone diseases) |
| Applicable area | Cell therapies and regenerative medicine products for osteonecrosis and intractable bone diseases |
| Quantitative Effects | At all time points of 4, 6 and 8 weeks after transplantation, the SHED group showed a significantly higher bone repair rate than the scaffold-only group. From 4 weeks after transplantation onward, the SHED group showed a significantly higher bone repair rate than the bone marrow-derived MSC group. |
| Source | Article published in the Journal of Orthopaedic Research, DOI: http://dx.doi.org/10.1002/jor.70263 |
Items this document does not state (10)
These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.
The reasons the company gives
The company's own explanation, not something inferred from the numbers.In a rat model of radiation-induced osteonecrosis, the SHED group showed a higher bone repair rate than both the scaffold-only group and the bone marrow-derived MSC group, indicating that SHED may promote angiogenesis and tissue repair.