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Other Disclosures4584Kidswell Bio CorporationPharmaceuticals

Research findings on an oncolytic virus therapy using SHED (SHED-OV therapy) published in an international academic journal

A study on the development of SHED-OV therapy, in which SHED is loaded with an oncolytic virus, and confirmation of its therapeutic effects in an animal model of malignant glioma has been published in an international academic journal. Clinical application remains a subject for future research.

Worth reading
73In focus
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Direction
Improvement
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Announced details

SHED-OV therapy (oncolytic virus therapy using SHED), SQ-SHED (SHED-based product)
Applicable field (uses covered by this announcement)

Cell therapy and gene-modified cell therapy for intractable brain tumors, including malignant glioma

What the company reported numerically
Quantitative Effects

In a mouse model of malignant glioma, the survival period of the SHED-OV treatment group was significantly longer than that of the control group. Tumors completely disappeared in 3 mice.

Relationship between the counterparty and the company
Kidswell Bio Corporation4584
Relationship with the Company

S-Quatre Co., Ltd. and Hamamatsu University School of Medicine conducted joint research. S-Quatre provided SHED. S-Quatre is a group company of Kidswell Bio Corporation.

CounterpartyHamamatsu University School of Medicine, National University Corporation

1-20-1 Handayama, Chuo-ku, Hamamatsu. A national university corporation with departments including neurosurgery.

Registration number and expiry date

DOI: 10.1038/s41417-026-01072-1

Impact on Business Performance

No impact on business performance stated

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

Cancer Gene Therapy

Announced details
ItemDetails
Names of Products / Services CoveredSHED-OV therapy (oncolytic virus therapy using SHED), SQ-SHED (SHED-based product)
CounterpartyHamamatsu University School of Medicine, National University Corporation
Counterparty overview1-20-1 Handayama, Chuo-ku, Hamamatsu. A national university corporation with departments including neurosurgery.
Relationship with the CompanyS-Quatre Co., Ltd. and Hamamatsu University School of Medicine conducted joint research. S-Quatre provided SHED. S-Quatre is a group company of Kidswell Bio Corporation.
Applicable areaCell therapy and gene-modified cell therapy for intractable brain tumors, including malignant glioma
Registration number and expiry dateDOI: 10.1038/s41417-026-01072-1
Quantitative EffectsIn a mouse model of malignant glioma, the survival period of the SHED-OV treatment group was significantly longer than that of the control group. Tumors completely disappeared in 3 mice.
Impact on Business PerformanceNo impact on business performance stated
SourceCancer Gene Therapy
Items this document does not state (9)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyLocationLocation scaleUsage history

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The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To deepen understanding of the characteristics and mechanisms of action of SHED and accumulate knowledge useful for future research and development.

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Research findings on an oncolytic virus therapy using SHED (SHED-OV therapy) published in an international academic journal | Kidswell Bio Corporation (4584) timely disclosure | Komori