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Business Alliances4583Chiome Bioscience Inc.Pharmaceuticals

Notice of Entering into a Joint Research Agreement with FRONTEO Corporation on AI Drug Discovery

Chiome Bioscience entered into a joint research agreement with FRONTEO to combine technology for identifying drug discovery targets using AI with technology for generating and evaluating antibodies, with the aim of creating drug candidates for bispecific antibodies.

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Agreements reached under this partnership

Business Alliances
4583Chiome Bioscience Inc.
Alliance partnerFRONTEO, Inc.
Details of the alliance
  1. 1

    FRONTEO will use DDAIF, its AI drug discovery platform, to analyze disease-related target molecules for each research theme and select multiple candidate combinations of targets considered promising for development as bispecific antibodies

  2. 2

    Chiome Bioscience will use DoppeLib™ to generate bispecific antibody candidates and evaluate their binding activity, function and other characteristics

  3. 3

    For promising candidates, the parties will advance optimization and validation while taking into consideration efficacy, safety and suitability as pharmaceuticals

  4. 4

    The two companies will conduct joint research on multiple research themes

  5. 5

    For the antibody drug candidates generated, the parties will seek to pursue joint development or prompt out-licensing to pharmaceutical companies and other parties

These are items that the documents state the two companies will work on. The lines above and below represent arrangements between the two companies.

Numerical targets under the alliance

Create bispecific antibody drug candidates during fiscal 2027

About the partner
Business DescriptionLife sciences AI, risk management, DX and other businesses utilizing the internally developed equation-driven AI system KIBIT
LocationMinato-ku, Tokyo
Share capital¥915.057 million (as of 30 June 2026)
Impact on Business Performance

The impact on results for the fiscal year ending December 2026 is expected to be immaterial.

Contract Date3 September 2026Alliance start date3 September 2026
Agreements reached under this partnership
ItemDetails
Name of alliance partnerFRONTEO, Inc.
Alliance partner's business activitiesLife sciences AI, risk management, DX and other businesses utilizing the internally developed equation-driven AI system KIBIT
Alliance partner's locationMinato-ku, Tokyo
Alliance partner's capital¥915.057 million (as of 30 June 2026)
Type of allianceBusiness Alliances
Details of the allianceFRONTEO will use DDAIF, its AI drug discovery platform, to analyze disease-related target molecules for each research theme and select multiple candidate combinations of targets considered promising for development as bispecific antibodies, Chiome Bioscience will use DoppeLib™ to generate bispecific antibody candidates and evaluate their binding activity, function and other characteristics, For promising candidates, the parties will advance optimization and validation while taking into consideration efficacy, safety and suitability as pharmaceuticals, The two companies will conduct joint research on multiple research themes, For the antibody drug candidates generated, the parties will seek to pursue joint development or prompt out-licensing to pharmaceutical companies and other parties
Numerical targets under the allianceCreate bispecific antibody drug candidates during fiscal 2027
Contract Date3 September 2026
Alliance start date3 September 2026
Impact on Business PerformanceThe impact on results for the fiscal year ending December 2026 is expected to be immaterial.
Items this document does not state (13)
Alliance partner's net salesAlliance partner's operating incomeNumber of shares acquiredAcquisition priceShareholding ratioOverview of the joint ventureOwnership ratioDispatch of directors and officersContract PeriodShareholding PolicyDate of board resolutionShare Acquisition Date and Payment DateChange in major shareholders

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To integrate FRONTEO's AI drug discovery support service for identifying novel targets with the Company's antibody drug discovery technology, enabling the continuous advancement of research from target identification through the creation and validation of antibody candidates.

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Notice of Entering into a Joint Research Agreement with FRONTEO Corporation on AI Drug Discovery | Chiome Bioscience Inc. (4583) timely disclosure | Komori