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Other Disclosures4582SymBio Pharmaceuticals LimitedPharmaceuticals

Notice of Acceptance of Results from the IV BCV Study in Malignant Brain Tumors (Glioblastoma) for Presentation at the 85th Annual Meeting of the Japanese Cancer Association

Preclinical study results for IV BCV in malignant brain tumors (glioblastoma) have been accepted for a poster presentation at the 85th Annual Meeting of the Japanese Cancer Association. The presentation is scheduled to report IV BCV accumulation in intracranial tumors and prolonged survival with monotherapy and in combination with standard therapy.

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Announced details

Brincidofovir (brincidofovir, IV BCV)
Applicable field (uses covered by this announcement)

Treatment of malignant brain tumors (glioblastoma, GBM). Monotherapy and combination therapy with standard treatment.

Launch date24 September 2026 (scheduled; conference poster presentation)
What the company reported numerically
Quantitative Effects

Accumulation in intracranial tumors was confirmed in a PDX model, and survival was significantly extended with monotherapy and combination therapy with standard treatment (specific figures are Not disclosed).

Relationship between the counterparty and the company
SymBio Pharmaceuticals Limited4582
Relationship with the Company

The parties are conducting joint research in the oncology field.

CounterpartyUniversity of California, San Francisco (UCSF), United States

University of California, San Francisco (UCSF), United States. Other information, including location, representative, and business activities, is Not disclosed.

Location (as indicated in this announcement)

Kyoto International Conference Center (Kyoto, Kyoto Prefecture)

Impact on Business Performance

There will be no impact on consolidated results for the fiscal year ending December 2026.

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

85th Annual Meeting of the Japanese Cancer Association

Announced details
ItemDetails
Names of Products / Services CoveredBrincidofovir (brincidofovir, IV BCV)
CounterpartyUniversity of California, San Francisco (UCSF), United States
Counterparty overviewUniversity of California, San Francisco (UCSF), United States. Other information, including location, representative, and business activities, is Not disclosed.
Relationship with the CompanyThe parties are conducting joint research in the oncology field.
Launch date24 September 2026 (scheduled; conference poster presentation)
Applicable areaTreatment of malignant brain tumors (glioblastoma, GBM). Monotherapy and combination therapy with standard treatment.
LocationKyoto International Conference Center (Kyoto, Kyoto Prefecture)
Quantitative EffectsAccumulation in intracranial tumors was confirmed in a PDX model, and survival was significantly extended with monotherapy and combination therapy with standard treatment (specific figures are Not disclosed).
Impact on Business PerformanceThere will be no impact on consolidated results for the fiscal year ending December 2026.
Source85th Annual Meeting of the Japanese Cancer Association
Items this document does not state (8)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleUsage history

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Because IV BCV accumulation in intracranial tumors and a significant extension of survival were confirmed in a PDX (patient-derived cancer cell) intracranial transplantation model.

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Notice of Acceptance of Results from the IV BCV Study in Malignant Brain Tumors (Glioblastoma) for Presentation at the 85th Annual Meeting of the Japanese Cancer Association | SymBio Pharmaceuticals Limited (4582) timely disclosure | Komori