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Other Disclosures4582SymBio Pharmaceuticals LimitedPharmaceuticals

Antitumor effects, mechanism of action, and sensitivity biomarkers of IV BCV in malignant lymphoma published in BMC Medicine

A collaborative study on the antitumor activity and mechanism of action of BCV (injectable brincidofovir) in malignant lymphoma models, as well as biomarkers for selecting patients expected to benefit from treatment, has been published in an academic journal.

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Improvement
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Announced details

IV BCV (injectable brincidofovir)
Applicable field (uses covered by this announcement)

NK/T-cell lymphoma, peripheral T-cell lymphoma, combination with immunotherapy, and hematologic and solid tumors

Relationship between the counterparty and the company
SymBio Pharmaceuticals Limited4582
Relationship with the Company

Collaborative research relationship. シンバイオ製薬 obtained the global license for BCV in September 2019.

CounterpartyNational Cancer Centre Singapore (NCCS)

National Cancer Centre Singapore (NCCS). Location, capital and year established: Not disclosed. The principal investigator is Dr. Jason Chan, a senior consultant in NCCS's Division of Medical Oncology and an associate professor at Duke-NUS Medical School.

Impact on Business Performance

The company explained that publication of the paper could accelerate development in the oncology field and help establish it as a new pillar of its growth strategy. The specific impact on financial results is Not disclosed.

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

Paper published in BMC Medicine, “Preclinical activity of brincidofovir in peripheral T-cell and NK/T-cell lymphoma.” DOI: 10.1186/s12916-026-04680-8

Announced details
ItemDetails
Names of Products / Services CoveredIV BCV (injectable brincidofovir)
CounterpartyNational Cancer Centre Singapore (NCCS)
Counterparty overviewNational Cancer Centre Singapore (NCCS). Location, capital and year established: Not disclosed. The principal investigator is Dr. Jason Chan, a senior consultant in NCCS's Division of Medical Oncology and an associate professor at Duke-NUS Medical School.
Relationship with the CompanyCollaborative research relationship. シンバイオ製薬 obtained the global license for BCV in September 2019.
Applicable areaNK/T-cell lymphoma, peripheral T-cell lymphoma, combination with immunotherapy, and hematologic and solid tumors
Impact on Business PerformanceThe company explained that publication of the paper could accelerate development in the oncology field and help establish it as a new pillar of its growth strategy. The specific impact on financial results is Not disclosed.
SourcePaper published in BMC Medicine, “Preclinical activity of brincidofovir in peripheral T-cell and NK/T-cell lymphoma.” DOI: 10.1186/s12916-026-04680-8
Items this document does not state (11)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleQuantitative EffectsUsage history

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The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The company disclosed the results of a collaborative study with the National Cancer Centre Singapore (NCCS). The company explained that these scientific findings could accelerate development in the oncology field and lead to a new pillar of its growth strategy.

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Antitumor effects, mechanism of action, and sensitivity biomarkers of IV BCV in malignant lymphoma published in BMC Medicine | SymBio Pharmaceuticals Limited (4582) timely disclosure | Komori