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Occurring Fact4576D.Western Therapeutics Institute, Inc.Pharmaceuticals

Notice Regarding Changes to Borrowing Agreements with Financial Covenants

The financial covenants under 2 commitment loan agreements with Mizuho Bank, Ltd. were amended to add requirements to maintain net assets above zero and fixed-term deposits at or above the outstanding loan balance. The amendment agreements were executed on 30 June 2026, and the Company expects the impact on its consolidated results for the fiscal year ending December 2026 to be minor.

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Changes to a Borrowing Agreement with Financial Covenants

Subject Entity

D.Western Therapeutics Institute, Inc. (the Company)

Target Locations / Products

Neurogenic pain treatment DW-5LBT and cell product for regenerative medicine DWR-2206

Occurrence30 June 2026 (date the amendment agreements were executed)
This disclosure08/03/2026
Cause

A discrepancy arose for these development-stage products between the development plans established when the loans were initially borrowed and the outlook for the launch timing.

Accounting period in which recognized

Fiscal year ending December 2026 (impact on the Company's consolidated results)

Impact on Earnings Forecast

The Company expects the impact on its consolidated results for the fiscal year ending December 2026 to be minor.

Outlook

The Company will maintain positive net assets on its unconsolidated and consolidated balance sheets as of the end of each fiscal year, and will maintain fixed-term deposits at or above the aggregate outstanding balance of borrowings from the lenders. The repayment due dates are 30 September 2029 and 30 June 2030.

Event that occurred
ItemDetails
Event nameChanges to a Borrowing Agreement with Financial Covenants
Date of occurrence30 June 2026 (date the amendment agreements were executed)
Subject EntityD.Western Therapeutics Institute, Inc. (the Company)
Target Locations / ProductsNeurogenic pain treatment DW-5LBT and cell product for regenerative medicine DWR-2206
CauseA discrepancy arose for these development-stage products between the development plans established when the loans were initially borrowed and the outlook for the launch timing.
Accounting period in which recognizedFiscal year ending December 2026 (impact on the Company's consolidated results)
Impact on Earnings ForecastThe Company expects the impact on its consolidated results for the fiscal year ending December 2026 to be minor.
OutlookThe Company will maintain positive net assets on its unconsolidated and consolidated balance sheets as of the end of each fiscal year, and will maintain fixed-term deposits at or above the aggregate outstanding balance of borrowings from the lenders. The repayment due dates are 30 September 2029 and 30 June 2030.
Items this document does not state (17)
Date recognized / date notice receivedAmount of Impact on Business PerformanceType of litigation or proceedingCourt or authorityPlaintiffDefendantDate of filing / date of actionClaim amount / surcharge amountAmount of receivables at risk of non-collection or delayed collectionSuspended operationsScheduled resumption dateInvestigation structureMeasures to prevent recurrenceDirectors' and officers' liabilityVoting rights ownership percentage before the changeVoting rights ownership percentage after the changePlanned follow-up disclosure

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

A discrepancy arose between the development plans established when the loans were initially borrowed and the outlook for the launch timing of the neurogenic pain treatment DW-5LBT and the cell product for regenerative medicine DWR-2206.

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Notice Regarding Changes to Borrowing Agreements with Financial Covenants | D.Western Therapeutics Institute, Inc. (4576) timely disclosure | Komori