Komori
Other Disclosures4571Nano Holdings,Inc.Pharmaceuticals

Research findings on a new mRNA drug have been announced by a group led by Professor Itaka Keiji (位高啓史).

A research group at a collaborating institution published findings in an international scientific journal showing that Col9 mRNA suppresses the onset and progression of osteoarthritis. The findings also indicated the potential for a new prevention and treatment method combining Col9 mRNA with RUNX1 mRNA, which is already undergoing a Phase 1 clinical trial in Australia.

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Announced details

RUNX1 mRNACol9 mRNAPolymeric micelles
Applicable field (uses covered by this announcement)

Prevention and treatment of osteoarthritis

Relationship between the counterparty and the company
Nano Holdings,Inc.4571
Relationship with the Company

株式会社PrimRNA, a subsidiary of NANO MRNA株式会社, is conducting a Phase 1 clinical trial of RUNX1 mRNA in Australia, while our company is conducting joint research and development with Professor Itaka Keiji (位髙 啓史).

CounterpartyOsaka University Research Institute for Infectious Diseases, and the research group led by Professor Itaka Keiji (位髙 啓史)

A research group led by Professor Itaka Keiji (位髙 啓史) at the Osaka University Research Institute for Infectious Diseases. Other information, including location, representative, business activities, capital and year established, is Not disclosed.

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

The international scientific journal Science Advances and the website of the Osaka University Research Institute for Infectious Diseases

Announced details
ItemDetails
Names of Products / Services CoveredRUNX1 mRNA, Col9 mRNA, Polymeric micelles
CounterpartyOsaka University Research Institute for Infectious Diseases, and the research group led by Professor Itaka Keiji (位髙 啓史)
Counterparty overviewA research group led by Professor Itaka Keiji (位髙 啓史) at the Osaka University Research Institute for Infectious Diseases. Other information, including location, representative, business activities, capital and year established, is Not disclosed.
Relationship with the Company株式会社PrimRNA, a subsidiary of NANO MRNA株式会社, is conducting a Phase 1 clinical trial of RUNX1 mRNA in Australia, while our company is conducting joint research and development with Professor Itaka Keiji (位髙 啓史).
Applicable areaPrevention and treatment of osteoarthritis
SourceThe international scientific journal Science Advances and the website of the Osaka University Research Institute for Infectious Diseases
Items this document does not state (12)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleQuantitative EffectsUsage historyImpact on Business Performance

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The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Research findings by the group led by Professor Itaka Keiji (位髙 啓史) were published in the international scientific journal Science Advances. The publication explains that Col9 mRNA and RUNX1 mRNA suppress the progression of osteoarthritis through different mechanisms.

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Research findings on a new mRNA drug have been announced by a group led by Professor Itaka Keiji (位高啓史). | Nano Holdings,Inc. (4571) timely disclosure | Komori