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Changes in Officers4571Nano Holdings,Inc.Pharmaceuticals

Notice Regarding Changes in Representative Directors, Changes in Executive Positions, the Company's New Structure as an Investment Company, and Executive Appointments at a Subsidiary

Effective 1 April 2026, the representative director position will change from Akinaga Shiro (秋永 士朗) to Matsuo Takashi (松尾 隆), with Akinaga Shiro (秋永 士朗) becoming a director and CTO. Matsuo Takashi (松尾 隆) will also serve as CFO, and from the same date the Company will transition to an investment holding company structure focused primarily on investment activities.

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Who is moving to which position

Resolved 18 March 2026

Incoming appointee

2 items
Scheduled Appointment DateEffective 1 April 2026
Akinaga Shiro (秋永 士朗)
Previous positionRepresentative Director, CTO (with representative authority)
New positionDirector, CTO (without representative authority)
Matsuo Takashi (松尾 隆)
Previous positionDirector, CAO / CCO
New positionDirector, CFO / CAO / CCO

Departing officer

1 item
Date of departureEffective 1 April 2026 (departure from the position of representative director)
Akinaga Shiro (秋永 士朗)Next role stated
Former PositionRepresentative Director, CTO (with representative authority)
New positionDirector, CTO (without representative authority)

“Next role stated” means the document names the position the person holds after stepping down. It does not necessarily mean they are leaving the company.

Whether the incumbent will remain in office (whether they will retain their position)

Continuing in office as Director

Directors after the change8Number
Reason for change

This change in representative authority is intended to clarify responsibility for the Company's investment business, as the Company will focus its main business on investment activities effective 1 April. Akinaga Shiro (秋永 士朗) will be responsible for the scientific evaluation of investment target companies and, as Representative Director and President of NANO MRNA株式会社, will oversee the NANO MRNA business. Matsuo Takashi (松尾 隆) will also serve as CFO, in addition to his existing positions as CAO and CCO, to strengthen the finance function in connection with the transition to investment activities.

Details of organizational changes

Effective 1 April 2026, the Company will transition to an investment company structure (investment holding company) and make investment activities its principal business. The Company will establish NANO MRNA株式会社 and launch an investment structure in cooperation with NBI and Nano Holdings US, LLC.

Who is moving to which position
ItemDetails
Resolution date18 March 2026
Scheduled Appointment DateEffective 1 April 2026
Date of departureEffective 1 April 2026 (departure from the position of representative director)
Name of appointeeAkinaga Shiro (秋永 士朗), Matsuo Takashi (松尾 隆)
Appointee's new positionDirector, CTO (without representative authority), Director, CFO / CAO / CCO
Appointee's previous positionRepresentative Director, CTO (with representative authority), Director, CAO / CCO
Name of departing officerAkinaga Shiro (秋永 士朗)
Former position of departing officerRepresentative Director, CTO (with representative authority)
New position of departing officerDirector, CTO (without representative authority)
Whether the incumbent will remain in officeContinuing in office as Director
Reason for changeThis change in representative authority is intended to clarify responsibility for the Company's investment business, as the Company will focus its main business on investment activities effective 1 April. Akinaga Shiro (秋永 士朗) will be responsible for the scientific evaluation of investment target companies and, as Representative Director and President of NANO MRNA株式会社, will oversee the NANO MRNA business. Matsuo Takashi (松尾 隆) will also serve as CFO, in addition to his existing positions as CAO and CCO, to strengthen the finance function in connection with the transition to investment activities.
Number of directors after the change8 directors (including 2 outside directors)
Details of organizational changesEffective 1 April 2026, the Company will transition to an investment company structure (investment holding company) and make investment activities its principal business. The Company will establish NANO MRNA株式会社 and launch an investment structure in cooperation with NBI and Nano Holdings US, LLC.
Items this document does not state (8)
Appointee's date of birthYear the appointee joined the CompanyNumber of shares held by the appointeeReason for departureReasons for appointmentFiling as an independent officerChange in Corporate Governance StructureSubject to Approval by the General Meeting of Shareholders

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

As the Company will focus its main business on investment activities effective 1 April, the change in representative authority is intended to clarify responsibility for this business. Akinaga Shiro (秋永 士朗) will be responsible for the scientific evaluation of investment target companies and the management of NANO MRNA株式会社, while Matsuo Takashi (松尾 隆) will also serve as CFO to strengthen the finance function in connection with the transition to investment activities.

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Notice Regarding Changes in Representative Directors, Changes in Executive Positions, the Company's New Structure as an Investment Company, and Executive Appointments at a Subsidiary | Nano Holdings,Inc. (4571) timely disclosure | Komori