Material uncertainty related to the going-concern assumption, operating losses and negative cash flow
First written in FY2018. 19 of 29 entries say "Worsened", first in FY2019-Q2. Latest entry: 2026-08-07.
OncoTherapy Science moved to the "Worse" side of this theme in 2019, 3 years before the typical company in this theme (2022).
The whole theme swung hardest in 2025: 2 of 11 companies on the "Worse" side.
5 other companies' latest entry also says "Mitigated".
- FY2026MitigatedAnnual report
「As of the end of the current consolidated fiscal year, the Group held ¥2,089 million in cash and deposits and determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
Although the situation giving rise to significant doubt about the going-concern assumption, operating losses and negative operating cash flow have continued, cash and deposits increased to ¥2,089 million, and the determination that no material uncertainty exists was maintained. - FY2026-H1MitigatedAnnual report
「As of the end of the current interim consolidated fiscal period, the Group held ¥1,675 million in cash and deposits and determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
Although the situation giving rise to significant doubt about the going-concern assumption has continued, cash and deposits increased from the end of the previous fiscal year, and the Group continued to determine that no material uncertainty exists. - FY2025RestatedAnnual report
「The Group will continue to promote the above measures and work to improve its earnings capacity and strengthen its financial position. However, these measures are currently being implemented, and the Group currently recognizes material uncertainty regarding the going-concern assumption.」
The situation giving rise to significant doubt about the going-concern assumption and material uncertainty have continued. Meanwhile, cash and cash equivalents increased to ¥833 million, and the measures are reported to be under implementation. - FY2024WorsenedAnnual report
「The Group will continue to promote the above measures and work to improve its earnings capacity and strengthen its financial position. However, these measures are currently being implemented, and the Group currently recognizes material uncertainty regarding the going-concern assumption.」
The situation giving rise to significant doubt about the going-concern assumption and material uncertainty have continued. Cash and cash equivalents decreased to ¥527 million, and measures including improving earnings capacity and raising funds are reported to be under implementation. - FY2024-Q3MaterialisedAnnual report
「At present, significant uncertainty regarding the going-concern assumption is recognized.」
As the situation giving rise to significant doubt about the going-concern assumption continued, the disclosure changed from the previous determination that no material uncertainty existed to a statement that material uncertainty currently exists. Cash and deposits stood at ¥881 million, and the method, amount and timing of additional funding remained undecided. - FY2024-Q2WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the second quarter of the current consolidated fiscal year, the Group held ¥881 million in cash and deposits as of that date and conducts research and development in line with the status of its funding. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
As the situation giving rise to significant doubt about the going-concern assumption continued, cash and deposits decreased from ¥912 million in FY2024-Q1 to ¥881 million. While the Group stated that research and development would be conducted in line with the status of its funding, it maintained its determination that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty exists. - FY2024-Q1WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the first quarter of the current consolidated fiscal year, the Group held ¥912 million in cash and deposits as of that date and conducts research and development in line with the status of its funding. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
As the situation giving rise to significant doubt about the going-concern assumption continued, cash and deposits decreased to ¥912 million, and the Group stated that research and development would be conducted in line with the status of its funding. Meanwhile, it maintained its determination that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty exists. - FY2023WorsenedAnnual report
「After a more conservative review, including the Group's future funding plans, the Group determined that, although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the current consolidated fiscal year, it held ¥1,117 million in cash and deposits as of that date. In addition, with respect to the issuance of new shares through a third-party allotment and the 34th and 35th Stock Acquisition Rights, with Long Corridor Alpha Opportunities Master Fund and MAP246 Segregated Portfolio as the allotment recipients, as resolved by the Company's Board of Directors on 24 March 2023, payment of the total issue amount (LCAO ¥76,760 thousand; MAP246 ¥19,190 thousand) was completed on 10 April 2023. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
The situation giving rise to significant doubt about the going-concern assumption has continued, and cash and deposits at the end of the period decreased to ¥1,117 million. The issuance and payment of new shares and stock acquisition rights through a third-party allotment are described as measures to address the situation. - FY2023-Q3WorsenedAnnual report
「After a more conservative review, including the Group's future funding plans, the Group determined that, although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the third quarter of the current consolidated fiscal year, it held ¥977 million in cash and deposits as of that date and had no concern about the continuity of its business activities for the foreseeable future. It therefore determined that no material uncertainty regarding the going-concern assumption exists.」
The situation giving rise to significant doubt about the going-concern assumption has continued. Cash and deposits decreased from ¥1,313 million at the end of the previous quarter to ¥977 million, and the explanation that approximately 1.5 years' worth of research and development expenses had been secured was also no longer included. - FY2023-Q2WorsenedAnnual report
「For these reasons, after a more conservative review, including the Group's future funding plans, the Group determined that, although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the second quarter of the current consolidated fiscal year, it held ¥1,313 million in cash and deposits as of that date and had no concern about the continuity of its business activities for the foreseeable future. It therefore determined that no material uncertainty regarding the going-concern assumption exists.」
As the situation giving rise to significant doubt about the going-concern assumption continued, cash and deposits decreased from ¥1,505 million at the end of the previous quarter to ¥1,313 million. The previous explanation that approximately 1.5 years' worth of research and development expenses had been secured was no longer included. - FY2023-Q1WorsenedAnnual report
「After a more conservative review, including the Group's future funding plans, the Group determined that, although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the first quarter of the current consolidated fiscal year, it held ¥1,505 million in cash and deposits as of that date and had no concern about the continuity of its business activities for the foreseeable future. It therefore determined that no material uncertainty regarding the going-concern assumption exists.」
The situation giving rise to significant doubt about the going-concern assumption has continued. Cash and deposits decreased from ¥1,836 million at the end of the previous consolidated fiscal year to ¥1,505 million, and the previous explanation that approximately 1.5 years' worth of research and development expenses had been secured was also no longer included. - FY2022WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the current consolidated fiscal year, the Group held ¥1,836 million in cash and deposits as of that date. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
As the situation giving rise to significant doubt about the going-concern assumption continued, cash and deposits decreased from ¥2,221 million at the end of the previous quarter to ¥1,836 million. The previous explanation that approximately 1.5 years' worth of research and development expenses had been secured was also no longer included. - FY2022-Q3WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the third quarter of the current consolidated fiscal year, the Group held ¥2,221 million in cash and deposits as of that date. It has determined that, by implementing the measures below, there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
The situation giving rise to significant doubt about the going-concern assumption has continued. Cash and deposits decreased from ¥3,122 million at the end of the previous quarter to ¥2,221 million, and the explanation that approximately 1.5 years' worth of research and development expenses had been secured was also no longer included. - FY2022-Q2WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the second quarter of the current consolidated fiscal year, the Group held ¥3,122 million in cash and deposits as of that date. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
The situation giving rise to significant doubt about the going-concern assumption has continued. Cash and deposits decreased from ¥3,136 million at the end of the previous quarter to ¥3,122 million, and the explanation that approximately 1.5 years' worth of research and development expenses had been secured was also no longer included. - FY2022-Q1WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the first quarter of the current consolidated fiscal year, the Group held ¥3,136 million in cash and deposits as of that date. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
The situation giving rise to significant doubt about the going-concern assumption has continued. Cash and deposits increased from ¥2,899 million at the end of the previous consolidated fiscal year to ¥3,136 million, while the previous explanation that approximately 1.5 years' worth of research and development expenses had been secured was no longer included. - FY2021-Q3WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the third quarter of the current consolidated fiscal year, the Group held ¥3,394 million in cash and deposits as of that date and had secured approximately 1.5 years' worth of research and development expenses. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
As the situation giving rise to significant doubt about the going-concern assumption continued, cash and deposits decreased from ¥3,729 million at the end of the previous quarter to ¥3,394 million. Meanwhile, the Group had secured approximately 1.5 years' worth of research and development expenses and continued to determine that no material uncertainty exists. - FY2021-Q2WorsenedAnnual report
「Although a situation that could give rise to significant doubt about the going-concern assumption existed at the end of the second quarter of the current consolidated fiscal year, the Group held ¥3,729 million in cash and deposits as of that date and had secured approximately 1.5 years' worth of research and development expenses. Accordingly, it has determined that there is no concern about the continuity of its business activities for the foreseeable future and that no material uncertainty regarding the going-concern assumption exists.」
As the situation giving rise to significant doubt about the going-concern assumption continued, cash and deposits decreased from ¥4,160 million at the end of the previous quarter to ¥3,729 million. Meanwhile, the Group had secured approximately 1.5 years' worth of research and development expenses and continued to determine that no material uncertainty exists. - FY2021-Q1WorsenedAnnual report
「Accordingly, at the end of the first quarter of the current consolidated fiscal year, after conducting a more conservative review that included future funding plans, the group determined that although circumstances existed that could raise material doubt about the going-concern assumption, it held ¥4,160 million in cash and deposits as of the end of the first quarter and had secured approximately 1.5 years' worth of research and development expenses. It therefore determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
The situation giving rise to significant doubt about the going-concern assumption has continued, and cash and deposits decreased from ¥4,713 million at the end of the previous consolidated fiscal year to ¥4,160 million. Meanwhile, the Group has secured approximately 1.5 years' worth of research and development expenses and continues to determine that no material uncertainty exists. - FY2020-Q3WorsenedAnnual report
「Although circumstances existed at the end of the third quarter of the current consolidated fiscal year that could raise material doubt about the going-concern assumption, the company held ¥4,470 million in cash and deposits as of the end of the third quarter and had secured approximately 1.5 years' worth of research and development expenses. It therefore determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
While circumstances giving rise to material doubt about the going-concern assumption continued to exist, cash and deposits declined from ¥4,530 million at the end of the previous quarter to ¥4,470 million. Approximately 1.5 years' worth of research and development expenses had been secured, and the company continued to determine that no material uncertainty existed. - FY2020-Q2WorsenedAnnual report
「Although circumstances existed at the end of the second quarter of the current consolidated fiscal year that could raise material doubt about the going-concern assumption, the company held ¥4,530 million in cash and deposits as of the end of the second quarter and had secured approximately 1.5 years' worth of research and development expenses.」
While circumstances giving rise to material doubt about the going-concern assumption continued to exist, cash and deposits declined from ¥4,632 million at the end of the previous quarter to ¥4,530 million. The company continued to determine that no material uncertainty existed. - FY2020-Q1WorsenedAnnual report
「Although circumstances existed at the end of the first quarter of the current consolidated fiscal year that could raise material doubt about the going-concern assumption, the company held ¥4,632 million in cash and deposits as of the end of the first quarter and had secured approximately 1.5 years' worth of research and development expenses. It therefore determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
While circumstances giving rise to material doubt about the going-concern assumption continued to exist, cash and deposits declined from ¥4,857 million at the end of the previous fiscal year to ¥4,632 million. The period covered by secured research and development expenses remained approximately 1.5 years, and the company continued to determine that no material uncertainty existed. - FY2019-Q3WorsenedAnnual report
「Accordingly, at the end of the third quarter of the current consolidated fiscal year, after conducting a more conservative review that included future funding plans, the group determined that although circumstances existed that could raise material doubt about the going-concern assumption, it held ¥4,877 million in cash and deposits as of the end of the third quarter and had secured approximately 1.5 years' worth of research and development expenses. It therefore determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
While circumstances giving rise to material doubt about the going-concern assumption continued to exist, cash and deposits declined from the previously reported ¥5,339 million to ¥4,877 million. Meanwhile, approximately 1.5 years' worth of research and development expenses had been secured, and the company continued to determine that no material uncertainty existed. - FY2019-Q2WorsenedAnnual report
「Although circumstances existed at the end of the second quarter of the current consolidated fiscal year that could raise material doubt about the going-concern assumption, the company held ¥5,339 million in cash and deposits as of the end of the second quarter and had secured approximately 1.5 years' worth of research and development expenses. It therefore determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
While circumstances giving rise to material doubt about the going-concern assumption continued to exist, cash and deposits declined from the previous ¥6,740 million to ¥5,339 million, and the period covered by secured research and development expenses shortened from approximately two years to 1.5 years. Meanwhile, the company continued to determine that no material uncertainty existed. - FY2019-Q1RestatedAnnual report
「Accordingly, at the end of the first quarter of the current consolidated fiscal year, after conducting a more conservative review that included future funding plans, the group determined that although circumstances existed that could raise material doubt about the going-concern assumption, it held ¥5,894 million in cash and deposits as of the end of the first quarter and had secured approximately two years' worth of research and development expenses. It therefore determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
The company stated that circumstances giving rise to material doubt about the going-concern assumption continued to exist against a backdrop of continuing operating losses and negative operating cash flow. Meanwhile, cash and deposits totaled ¥5,894 million, approximately two years' worth of research and development expenses had been secured, and the company continued to determine that no material uncertainty existed. - FY2018First statedAnnual report
「At the end of the consolidated fiscal year, after conducting a more conservative review that included future funding plans, the group determined that although circumstances existed that could raise material doubt about the going-concern assumption, it held ¥6,740 million in cash and deposits as of the end of the consolidated fiscal year and had secured approximately two years' worth of research and development expenses. Accordingly, it determined that there was no concern about the continuity of business activities for the time being and that no material uncertainty regarding the going-concern assumption existed.」
Against a backdrop of continuing operating losses and negative operating cash flow, circumstances giving rise to material doubt about the going-concern assumption were disclosed for the first time. Meanwhile, the group had secured ¥6,740 million in cash and deposits and approximately two years' worth of research and development expenses, and determined that no material uncertainty existed.