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Other Disclosures4506Sumitomo Pharma Co.,Ltd.Pharmaceuticals

Notice of the Presentation of Clinical Data on SMP-3124LP, a Novel Liposomal CHK1 Inhibitor in Development as an Anticancer Drug, at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting

Sumitomo Pharma America, Inc., the Company's US subsidiary, presented the first clinical data on SMP-3124LP, a liposomal CHK1 inhibitor in development, at ASCO 2026. The phase 1/2 study in patients with advanced solid tumors is ongoing, and preliminary results on antitumor activity and safety were presented.

Worth reading
71In focus
0–100. This measures how worthwhile something is to read, not how good or bad the company is.
Direction
Mixed performance
Direction inferred from the company’s description.
Scale
61
Example (number of patients in phase 1, as of April 2026)
Wording
Conditional
How definitive the wording is.

Announced details

SMP-3124LP (novel liposomal CHK1 inhibitor, injectable formulation)
Applicable field (uses covered by this announcement)

Anticancer drug, advanced solid tumors, platinum-resistant ovarian cancer, anal squamous cell carcinoma, and colorectal cancer with FBXW7 mutations

What the company reported numerically
Quantitative Effects

Disease control rate of 48.2%, 5 partial responses, 22 cases of stable disease, an 88% reduction in CA-125, a half-life of 24 to 28 hours, and a volume of distribution of 2.00 to 2.67 L

Usage history

61 patients with advanced solid tumors enrolled in phase 1 (as of April 2026), of whom 56 were evaluable for efficacy

Relationship between the counterparty and the company
Sumitomo Pharma Co.,Ltd.4506
Relationship with the Company

Sumitomo Pharma America, Inc., Sumitomo Pharma's US subsidiary, presented clinical data at ASCO 2026.

CounterpartyAmerican Society of Clinical Oncology (ASCO)

The American Society of Clinical Oncology. Its 2026 Annual Meeting will be held in Chicago, US, from 29 May to 2 June 2026.

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

Clinical data presented at the 2026 ASCO Annual Meeting

Announced details
ItemDetails
Names of Products / Services CoveredSMP-3124LP (novel liposomal CHK1 inhibitor, injectable formulation)
CounterpartyAmerican Society of Clinical Oncology (ASCO)
Counterparty overviewThe American Society of Clinical Oncology. Its 2026 Annual Meeting will be held in Chicago, US, from 29 May to 2 June 2026.
Relationship with the CompanySumitomo Pharma America, Inc., Sumitomo Pharma's US subsidiary, presented clinical data at ASCO 2026.
Applicable areaAnticancer drug, advanced solid tumors, platinum-resistant ovarian cancer, anal squamous cell carcinoma, and colorectal cancer with FBXW7 mutations
Quantitative EffectsDisease control rate of 48.2%, 5 partial responses, 22 cases of stable disease, an 88% reduction in CA-125, a half-life of 24 to 28 hours, and a volume of distribution of 2.00 to 2.67 L
Usage history61 patients with advanced solid tumors enrolled in phase 1 (as of April 2026), of whom 56 were evaluable for efficacy
SourceClinical data presented at the 2026 ASCO Annual Meeting
Items this document does not state (10)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To provide an update on the clinical development of SMP-3124LP and the presentation of its first clinical data at ASCO 2026. The Company states that formulating the drug as liposomal nanoparticles may expand its therapeutic window and optimize drug delivery to tumors while limiting exposure to normal tissue.

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Notice of the Presentation of Clinical Data on SMP-3124LP, a Novel Liposomal CHK1 Inhibitor in Development as an Anticancer Drug, at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting | Sumitomo Pharma Co.,Ltd. (4506) timely disclosure | Komori