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Other Disclosures2370MEDINET Co.,Ltd.Information and Communications, Services and Others

Research Findings on Novel CAR-T Cells Using HLH Peptides Presented at the 23rd Annual Scientific Meeting of the Japanese Society for Immunotherapy

In a joint research project with Osaka Metropolitan University, a novel CAR-T cell was developed using an HLH peptide in the antigen-recognition domain that distinguishes cancer cells and other target cells, and its ability to attack target cells was confirmed. Going forward, the company plans to compare it with conventional CAR-T cells and pursue applications to regenerative medicine products and technology licensing.

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Announced details

Novel CAR-T cells using an HLH peptide in the antigen-recognition domain
Applicable field (uses covered by this announcement)

Regenerative medicine products and CAR-T cell therapy

What the company reported numerically
Quantitative Effects

Not disclosed (cytotoxic activity and persistence of activity in some HLH-CAR-αβT cells were confirmed)

Relationship between the counterparty and the company
MEDINET Co.,Ltd.2370
Relationship with the Company

The company is conducting joint research with Osaka Metropolitan University.

CounterpartyOsaka Metropolitan University

A university to which the group of Specially Appointed Professor Ikuo Fujii, who is advancing the development of HLH peptides, belongs. Other information, including its location, representative, capital and year of establishment, is not disclosed.

Location (as indicated in this announcement)

Kyoto University Shiran Kaikan (venue for the academic meeting)

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

23rd Annual Meeting of the Japanese Society for Immunotherapy

Announced details
ItemDetails
Names of Products / Services CoveredNovel CAR-T cells using an HLH peptide in the antigen-recognition domain
CounterpartyOsaka Metropolitan University
Counterparty overviewA university to which the group of Specially Appointed Professor Ikuo Fujii, who is advancing the development of HLH peptides, belongs. Other information, including its location, representative, capital and year of establishment, is not disclosed.
Relationship with the CompanyThe company is conducting joint research with Osaka Metropolitan University.
Applicable areaRegenerative medicine products and CAR-T cell therapy
LocationKyoto University Shiran Kaikan (venue for the academic meeting)
Quantitative EffectsNot disclosed (cytotoxic activity and persistence of activity in some HLH-CAR-αβT cells were confirmed)
Source23rd Annual Meeting of the Japanese Society for Immunotherapy
Items this document does not state (10)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

Antigen-specific cytotoxic activity was confirmed in both αβ T cells and γδ T cells using CAR-T cells incorporating an HLH peptide, and persistence of activity was also demonstrated in some cases.

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Research Findings on Novel CAR-T Cells Using HLH Peptides Presented at the 23rd Annual Scientific Meeting of the Japanese Society for Immunotherapy | MEDINET Co.,Ltd. (2370) timely disclosure | Komori