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Other Disclosures2158FRONTEO,Inc.Information and Communications, Services and Others

FRONTEO and TagCyx Biotechnologies: launch second joint initiative toward the therapeutic application of next-generation nucleic acid aptamers using AI

FRONTEO and TagCyx Biotechnologies Inc. launched a second joint initiative to create and validate novel aptamers and explore indications for next-generation nucleic acid aptamers, based on the results of the initial AI analysis. Applications in apheresis, as well as pharmaceuticals, are also being considered.

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Announced details

Drug Discovery AI Factory(DDAIF)Xenoligo® (next-generation nucleic acid aptamer platform)Next-generation nucleic acid aptamers
Applicable field (uses covered by this announcement)
Drug DiscoveryPharmaceuticalsDiagnostic technologyApheresis (blood purification therapy)
Launch date10 November 2026 (second initiative launched; actual date)
Contract DateJanuary 2026 (PoC agreement; the body of the disclosure does not specify the exact date, while the related release cited in the footnote is dated 22 January 2026)
What the company reported numerically
Usage history

DDAIF has been adopted by multiple major pharmaceutical companies (cumulative number: Not disclosed)

Relationship between the counterparty and the company
FRONTEO,Inc.2158
Relationship with the Company

In January 2026, the companies entered into a proof-of-concept (PoC) agreement covering the exploration of novel target molecules and indications for next-generation nucleic acid aptamers. The companies will now jointly undertake a second research and development initiative.

CounterpartyTagCyx Biotechnologies Inc.

Based in Meguro-ku, Tokyo, and led by President and Representative Director Koseki Chizuko (古関 千寿子), this University of Tokyo startup develops pharmaceuticals and diagnostic technologies using next-generation nucleic acid aptamers based on artificial base-pair technology.

Registration number and expiry date

FRONTEO has obtained 21 patent rights in total in Japan, Europe, the United States and South Korea for technologies related to DDAIF (individual patent numbers and expiration dates: Not disclosed)

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Announced details
ItemDetails
Names of Products / Services CoveredDrug Discovery AI Factory(DDAIF), Xenoligo® (next-generation nucleic acid aptamer platform), Next-generation nucleic acid aptamers
CounterpartyTagCyx Biotechnologies Inc.
Counterparty overviewBased in Meguro-ku, Tokyo, and led by President and Representative Director Koseki Chizuko (古関 千寿子), this University of Tokyo startup develops pharmaceuticals and diagnostic technologies using next-generation nucleic acid aptamers based on artificial base-pair technology.
Relationship with the CompanyIn January 2026, the companies entered into a proof-of-concept (PoC) agreement covering the exploration of novel target molecules and indications for next-generation nucleic acid aptamers. The companies will now jointly undertake a second research and development initiative.
Contract DateJanuary 2026 (PoC agreement; the body of the disclosure does not specify the exact date, while the related release cited in the footnote is dated 22 January 2026)
Launch date10 November 2026 (second initiative launched; actual date)
Applicable areaDrug Discovery, Pharmaceuticals, Diagnostic technology, Apheresis (blood purification therapy)
Registration number and expiry dateFRONTEO has obtained 21 patent rights in total in Japan, Europe, the United States and South Korea for technologies related to DDAIF (individual patent numbers and expiration dates: Not disclosed)
Usage historyDDAIF has been adopted by multiple major pharmaceutical companies (cumulative number: Not disclosed)
Items this document does not state (9)
Contract ValueOffering priceAward/certification nameAwarding / certifying bodyLocationLocation scaleQuantitative EffectsImpact on Business PerformanceSource

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The initial AI analysis project identified multiple candidate diseases and targets, hypotheses regarding mechanisms of action, and candidates that could lead to applications in apheresis.

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FRONTEO and TagCyx Biotechnologies: launch second joint initiative toward the therapeutic application of next-generation nucleic acid aptamers using AI | FRONTEO,Inc. (2158) timely disclosure | Komori