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Other Disclosures2158FRONTEO,Inc.Information and Communications, Services and Others

University of Oklahoma confirms cell proliferation-inhibitory effects of novel pancreatic cancer target molecule candidates discovered by FRONTEO's Drug Discovery AI Factory service

The University of Oklahoma conducted cell experiments on new pancreatic cancer therapeutic target candidates identified by FRONTEO's AI and confirmed proliferation-inhibitory effects across multiple pancreatic cancer cell lines. The research is expected to proceed to animal studies.

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Announced details

Drug Discovery AI Factory(DDAIF)KIBIT (Kibit)
Applicable field (uses covered by this announcement)

Drug discovery research and pharmaceutical development for pancreatic cancer

Launch dateJuly 2025 (joint research commenced; actual date)
What the company reported numerically
Quantitative Effects

FRONTEO extracted 17 genes from approximately 20,000 human genes in about 2 days and confirmed cell proliferation-inhibitory effects for 6 of them. The University of Oklahoma also confirmed proliferation-inhibitory effects in multiple pancreatic cancer-derived cell lines.

Usage history

DDAIF has already been adopted by multiple major pharmaceutical companies and is building a track record.

Relationship between the counterparty and the company
FRONTEO,Inc.2158
Relationship with the Company

Joint research has been underway since July 2025. FRONTEO is responsible for identifying drug discovery target candidates and generating hypotheses concerning disease mechanisms, while the University of Oklahoma is responsible for validating their biological efficacy.

CounterpartyUniversity of Oklahoma College of Medicine (United States)

A medical research institution that is home to OU Health Stephenson Cancer Center, a National Cancer Institute (NCI)-designated cancer center. It is currently conducting more than 300 clinical trials and over 400 cancer research projects. The joint research is being conducted by the laboratory of Takebe Naoko (武部 直子), Professor of Hematology and Oncology.

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

OU Health Stephenson Cancer Center, Cancer Clinical Trials

OU Health Stephenson Cancer Center, Cancer Research

National Cancer Center Japan, “Latest Cancer Statistics”

Announced details
ItemDetails
Names of Products / Services CoveredDrug Discovery AI Factory(DDAIF), KIBIT (Kibit)
CounterpartyUniversity of Oklahoma College of Medicine (United States)
Counterparty overviewA medical research institution that is home to OU Health Stephenson Cancer Center, a National Cancer Institute (NCI)-designated cancer center. It is currently conducting more than 300 clinical trials and over 400 cancer research projects. The joint research is being conducted by the laboratory of Takebe Naoko (武部 直子), Professor of Hematology and Oncology.
Relationship with the CompanyJoint research has been underway since July 2025. FRONTEO is responsible for identifying drug discovery target candidates and generating hypotheses concerning disease mechanisms, while the University of Oklahoma is responsible for validating their biological efficacy.
Launch dateJuly 2025 (joint research commenced; actual date)
Applicable areaDrug discovery research and pharmaceutical development for pancreatic cancer
Quantitative EffectsFRONTEO extracted 17 genes from approximately 20,000 human genes in about 2 days and confirmed cell proliferation-inhibitory effects for 6 of them. The University of Oklahoma also confirmed proliferation-inhibitory effects in multiple pancreatic cancer-derived cell lines.
Usage historyDDAIF has already been adopted by multiple major pharmaceutical companies and is building a track record.
SourceOU Health Stephenson Cancer Center, Cancer Clinical Trials, OU Health Stephenson Cancer Center, Cancer Research, National Cancer Center Japan, “Latest Cancer Statistics”
Items this document does not state (9)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocationLocation scaleImpact on Business Performance

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The company's own explanation, not something inferred from the numbers.

Results supporting FRONTEO's preliminary tests were obtained as a specific advance in the joint research between FRONTEO and the University of Oklahoma.

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University of Oklahoma confirms cell proliferation-inhibitory effects of novel pancreatic cancer target molecule candidates discovered by FRONTEO's Drug Discovery AI Factory service | FRONTEO,Inc. (2158) timely disclosure | Komori