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Other Disclosures190AChordia Therapeutics Inc.Pharmaceuticals

Notice of Publication of a Paper on Joint Research Results Concerning MALT1

Findings from collaborative research with Miyazaki University, Kyoto University, the National Cancer Center and others on MALT1 inhibitors were published in the international academic journal iScience. The study found that MALT1 activity is important for tumor growth in some cases of adult T-cell leukemia/lymphoma, and that MALT1 inhibition had antitumor effects.

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52Recurring
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Improvement
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Announced details

MALT1 inhibitor ocipumaltib (CTX-177)
Applicable field (uses covered by this announcement)

Adult T-cell leukemia/lymphoma (ATL)

Relationship between the counterparty and the company
Chordia Therapeutics Inc.190A
Relationship with the Company

Collaborative research related to MALT1. The research was conducted with support from AMED's Industry-Academia Collaborative Medical Innovation Creation Program (ACT-M).

CounterpartyMiyazaki UniversityKyoto UniversityNational Cancer CenterJapan Agency for Medical Research and Development (AMED)

Professor Seiji Ogawa (小川誠司) of the Kyoto University Graduate School of Medicine is the principal investigator. AMED is a public agency that supported this collaborative research. Details of the other counterparties are not disclosed.

Location (as indicated in this announcement)

Fujisawa, Kanagawa Prefecture (the company's head office)

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

iScience, an international academic journal published by Cell Press; paper titled “The requirement of MALT1 activity for the growth of adult T cell leukemia/lymphoma”

Announced details
ItemDetails
Names of Products / Services CoveredMALT1 inhibitor ocipumaltib (CTX-177)
CounterpartyMiyazaki University, Kyoto University, National Cancer Center, Japan Agency for Medical Research and Development (AMED)
Counterparty overviewProfessor Seiji Ogawa (小川誠司) of the Kyoto University Graduate School of Medicine is the principal investigator. AMED is a public agency that supported this collaborative research. Details of the other counterparties are not disclosed.
Relationship with the CompanyCollaborative research related to MALT1. The research was conducted with support from AMED's Industry-Academia Collaborative Medical Innovation Creation Program (ACT-M).
Applicable areaAdult T-cell leukemia/lymphoma (ATL)
LocationFujisawa, Kanagawa Prefecture (the company's head office)
SourceiScience, an international academic journal published by Cell Press; paper titled “The requirement of MALT1 activity for the growth of adult T cell leukemia/lymphoma”
Items this document does not state (11)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleQuantitative EffectsUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The collaborative research findings were published on 23 July 2026 in iScience, an international academic journal published by Cell Press. The findings are also considered to contribute to further advances in the research and development of MALT1 inhibitors.

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Notice of Publication of a Paper on Joint Research Results Concerning MALT1 | Chordia Therapeutics Inc. (190A) timely disclosure | Komori