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Other Disclosures190AChordia Therapeutics Inc.Pharmaceuticals

Notice of the publication of a paper on a proof-of-concept study for AI-driven discovery of novel molecular scaffolds

A paper summarizing research into using AI to create novel chemical scaffolds was published online in ChemMedChem. The study involved designing and synthesizing novel compounds and confirming inhibitory activity against PI3Kα.

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Announced details

DeepSARMBoltz-2PI3K/mTOR inhibitors
Applicable field (uses covered by this announcement)

Drug discovery research, medicinal chemistry, and discovery of novel chemical scaffolds for PI3K/mTOR inhibitors

What the company reported numerically
Quantitative Effects

Inhibitory activity against PI3Kα was demonstrated (figures not disclosed).

Relationship between the counterparty and the company
Chordia Therapeutics Inc.190A
Relationship with the Company

The research results were generated in collaboration with the research team. Capital and personnel relationships are not disclosed.

Counterparty株式会社理論創薬研究所Axcelead Drug Discovery Partners株式会社

株式会社理論創薬研究所 is the research institution and company that developed DeepSARM, an AI-based drug discovery platform. Axcelead Drug Discovery Partners株式会社 is identified as a research team. Other information, including location, representative, business activities, capital and year of establishment, is not disclosed.

Location (as indicated in this announcement)

Fujisawa, Kanagawa Prefecture (the company's head office)

Impact on Business Performance

By extending the technology to drug discovery targets in new pipelines, it is expected to contribute to the creation of novel compounds and greater efficiency in drug discovery research.

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

ChemMedChem, Wiley, and Chemistry Europe

Announced details
ItemDetails
Names of Products / Services CoveredDeepSARM, Boltz-2, PI3K/mTOR inhibitors
Counterparty株式会社理論創薬研究所, Axcelead Drug Discovery Partners株式会社
Counterparty overview株式会社理論創薬研究所 is the research institution and company that developed DeepSARM, an AI-based drug discovery platform. Axcelead Drug Discovery Partners株式会社 is identified as a research team. Other information, including location, representative, business activities, capital and year of establishment, is not disclosed.
Relationship with the CompanyThe research results were generated in collaboration with the research team. Capital and personnel relationships are not disclosed.
Applicable areaDrug discovery research, medicinal chemistry, and discovery of novel chemical scaffolds for PI3K/mTOR inhibitors
LocationFujisawa, Kanagawa Prefecture (the company's head office)
Quantitative EffectsInhibitory activity against PI3Kα was demonstrated (figures not disclosed).
Impact on Business PerformanceBy extending the technology to drug discovery targets in new pipelines, it is expected to contribute to the creation of novel compounds and greater efficiency in drug discovery research.
SourceChemMedChem, Wiley, and Chemistry Europe
Items this document does not state (9)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleUsage history

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To validate the effectiveness of the novel chemical scaffold discovery technology and demonstrate its potential to efficiently generate new chemical structures that are difficult to identify through conventional drug discovery research.

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Notice of the publication of a paper on a proof-of-concept study for AI-driven discovery of novel molecular scaffolds | Chordia Therapeutics Inc. (190A) timely disclosure | Komori