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Other Disclosures190AChordia Therapeutics Inc.Pharmaceuticals

Notice of Publication of a Paper on the Discovery of the CDK12 Inhibitor CTX-439

A paper summarizing the results of medicinal chemistry research on CTX-439, a CDK12 inhibitor in preclinical development, was published online in ACS Medicinal Chemistry Letters.

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Announced details

CDK12 inhibitor CTX-439
Applicable field (uses covered by this announcement)

Cancer drug development and drug discovery research targeting transcriptional regulation in cancer cells

Launch date23 June 2026 (paper published online, actual)
Relationship between the counterparty and the company
Chordia Therapeutics Inc.190A
Relationship with the Company

Our company led the research and generated the research results in collaboration with the research teams of Takeda Pharmaceutical Company Limited and Axcelead Drug Discovery Partners株式会社.

CounterpartyTakeda Pharmaceutical Company LimitedAxcelead Drug Discovery Partners株式会社ACS Medicinal Chemistry Letters

The research teams of Takeda Pharmaceutical Company Limited and Axcelead Drug Discovery Partners株式会社. ACS Medicinal Chemistry Letters is an international academic journal published by the American Chemical Society (ACS). Other information on locations, representatives, paid-in capital and year of establishment is Not disclosed.

Location (as indicated in this announcement)

Fujisawa, Kanagawa Prefecture (the company's head office)

In this announcement the company addresses none of Contract Value / Offering price / Impact on Business Performance.

Source (materials cited by the company)

ACS Medicinal Chemistry Letters, the paper “Discovery of CTX-439: A Potent and Selective CDK12 Inhibitor as a Prospective Anti-Cancer Drug,” DOI: 10.1021/acsmedchemlett.6c00138

Announced details
ItemDetails
Names of Products / Services CoveredCDK12 inhibitor CTX-439
CounterpartyTakeda Pharmaceutical Company Limited, Axcelead Drug Discovery Partners株式会社, ACS Medicinal Chemistry Letters
Counterparty overviewThe research teams of Takeda Pharmaceutical Company Limited and Axcelead Drug Discovery Partners株式会社. ACS Medicinal Chemistry Letters is an international academic journal published by the American Chemical Society (ACS). Other information on locations, representatives, paid-in capital and year of establishment is Not disclosed.
Relationship with the CompanyOur company led the research and generated the research results in collaboration with the research teams of Takeda Pharmaceutical Company Limited and Axcelead Drug Discovery Partners株式会社.
Launch date23 June 2026 (paper published online, actual)
Applicable areaCancer drug development and drug discovery research targeting transcriptional regulation in cancer cells
LocationFujisawa, Kanagawa Prefecture (the company's head office)
SourceACS Medicinal Chemistry Letters, the paper “Discovery of CTX-439: A Potent and Selective CDK12 Inhibitor as a Prospective Anti-Cancer Drug,” DOI: 10.1021/acsmedchemlett.6c00138
Items this document does not state (10)
Contract ValueOffering priceContract DateAward/certification nameAwarding / certifying bodyRegistration number and expiry dateLocation scaleQuantitative EffectsUsage historyImpact on Business Performance

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

To report the research results that led to the discovery of CTX-439.

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Notice of Publication of a Paper on the Discovery of the CDK12 Inhibitor CTX-439 | Chordia Therapeutics Inc. (190A) timely disclosure | Komori