Komori
Other Disclosures190AChordia Therapeutics Inc.Pharmaceuticals

Notice of Publication of a Paper on the First-in-Human Phase 1 Clinical Trial in Japan of the CLK Inhibitor Rogocekib for Solid Tumors

A paper summarizing the final results from the solid tumor cohort of the Japanese Phase 1 trial of Rogocekib (CTX-712) has been published in Clinical Cancer Research. Partial responses were observed in 3 patients with ovarian cancer, and the results indicated that MYC gene amplification may be a predictive biomarker of response.

Worth reading
67In focus
Scored from 5 of 6 sections
Direction
Improvement
Direction inferred from the company’s description.
Scale
46
Example
Wording
Conditional
How definitive the wording is.

Announced details

rogocekib(CTX-712)
Applicable field (uses covered by this announcement)

Advanced, relapsed and refractory solid tumors, particularly ovarian cancer

What the company reported numerically
Quantitative Effects

Partial responses (PR) were observed in 3 patients with ovarian cancer, and MYC gene amplification was confirmed in 2 of them

Usage history

Administered to a total of 46 patients with solid tumors

Relationship between the counterparty and the company
Chordia Therapeutics Inc.190A
Relationship with the Company

Relationship with the academic journal that published the clinical trial results for rogocekib developed by the Company

CounterpartyClinical Cancer Research

An academic journal publishing clinical and translational cancer research that connects basic research with clinical practice

Registration number and expiry date

jRCT2080224127

Impact on Business Performance

The Company believes that these results support the potential for future expansion of the indications for solid tumors

The company does not address Contract Value / Offering price.

Source (materials cited by the company)

Clinical Cancer Research、jRCT2080224127

Announced details
ItemDetails
Names of Products / Services Coveredrogocekib(CTX-712)
CounterpartyClinical Cancer Research
Counterparty overviewAn academic journal publishing clinical and translational cancer research that connects basic research with clinical practice
Relationship with the CompanyRelationship with the academic journal that published the clinical trial results for rogocekib developed by the Company
Applicable areaAdvanced, relapsed and refractory solid tumors, particularly ovarian cancer
Registration number and expiry datejRCT2080224127
Quantitative EffectsPartial responses (PR) were observed in 3 patients with ovarian cancer, and MYC gene amplification was confirmed in 2 of them
Usage historyAdministered to a total of 46 patients with solid tumors
Impact on Business PerformanceThe Company believes that these results support the potential for future expansion of the indications for solid tumors
SourceClinical Cancer Research、jRCT2080224127
Items this document does not state (8)
Contract ValueOffering priceContract DateLaunch dateAward/certification nameAwarding / certifying bodyLocationLocation scale

These are items the company does not state in this document. We do not leave them blank, nor fill them in from other sources or by inference.

The reasons the company gives

The company's own explanation, not something inferred from the numbers.

The final results from the solid tumor cohort were published in Clinical Cancer Research. The Company believes that these results support the potential for future expansion of the indications for solid tumors, including ovarian cancer.

How to read this page

This is not the documentKomori reads the disclosure the company filed and writes this summary. Figures are as stated by the company and are not audited.
Weight is not a verdictIt measures how much this changes what the company had already told the market. It is not a view on the shares.
Corrections happenIf the company reissues this disclosure, the page is rebuilt from the corrected version and the revision number moves up.
Notice of Publication of a Paper on the First-in-Human Phase 1 Clinical Trial in Japan of the CLK Inhibitor Rogocekib for Solid Tumors | Chordia Therapeutics Inc. (190A) timely disclosure | Komori